Water-Soluble Palladium Nanoclusters as Catalysts in Ligand-Free Suzuki-Miyaura Cross-Coupling Reactions

Priya Karna, Micheal Okeke, Debora Motta Meira, Zou Finfrock, Dong Sheng Yang

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


This Letter reports Pd-nanocluster catalysts and their formation in ligand-free Suzuki-Miyaura reactions with palladium(II) nitrate as a precatalyst. The catalysts are water-soluble neutral Pd tetramer and trimer in their singlet electronic states, as identified by UV-vis absorption spectroscopy, and are formed by leaching of spherical Pd(0) nanoparticles with an average diameter of about 3 nm. The Pd(0) nanoparticles are produced by reducing palladium(II) nitrate and characterized with transmission electron microscopy and Pd K-edge extended X-ray fine structure spectroscopy. The Pd(II) reduction is induced by ethanol, enhanced by potassium hydroxide, and monitored with X-ray photoelectron spectroscopy.

Original languageEnglish
Pages (from-to)3188-3193
Number of pages6
JournalACS Applied Nano Materials
Issue number3
StatePublished - Mar 25 2022

Bibliographical note

Funding Information:
We acknowledge financial support from the National Science Foundation Division of Chemistry (Chemical Structure, Dynamics, and Mechanisms; Grant 1800316). This research used resources of the Advanced Photon Source, an Office of Science User Facility operated for the U.S. Department of Energy (DOE) Office of Science by Argonne National Laboratory, and was supported by the U.S. DOE under Contract DE-AC02-06CH11357 and the Canadian Light Source and its funding partners. The authors also thank Dali Qian and Jillian Cramer for their help with TEM.

Publisher Copyright:
© 2022 American Chemical Society. All rights reserved.


  • Pd nanoclusters
  • Pd(II) reduction
  • UV-vis spectroscopy
  • X-ray absorption spectroscopy
  • X-ray photoelectron spectroscopy
  • cross-coupling
  • homogeneous catalysis

ASJC Scopus subject areas

  • Materials Science (all)


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