Wegener's granulomatosis in a pediatric patient

Don Hayes, Joseph A. Iocono, Jeffery S. Bennett, David Corey Lachman, Hubert O. Ballard

Research output: Contribution to journalArticlepeer-review


Wegener's Granulomatosis (WG) is characterized by the clinical triad of upper and lower respiratory disease and renal insufficiency. Because WG masquerades as a syndrome its diagnosis is often delayed. Astute clinicians should include WG in their differential diagnosis when a patient presents with these classic findings. The diagnosis is a clinicopathologic one made by biopsy of appropriate tissue showing necrotizing granulomatous vasculitis. Lung tissue obtained by open thoracotomy has the highest diagnostic yield. At one time a universally fatal illness WG is now treatable with cyclophosphamide and prednisone therapy with remission in most cases. The authors present a case report of a pediatric patient who was eventually diagnosed with WG. The case serves as a reminder to all clinicians to keep this entity as a part of their diagnostic armamentarium.

Original languageEnglish
Pages (from-to)563-565
Number of pages3
JournalThe Journal of the Oklahoma State Medical Association
Issue number12
StatePublished - Dec 2003

ASJC Scopus subject areas

  • General Medicine


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