What Is a Cytokine Storm and Should It Matter to Me?

Jennifer Simkin, Tierra Strange, Nicholas Leblanc, Jessica C. Rivera

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

The recent COVID-19 pandemic has brought attention to cytokines and the phenomenon of cytokine storm into mainstream discussions. In this disease specifically, a cytokine storm overwhelming immune response contributes to the pathophysiology and mortality of the COVID-19 infection. Analogous perturbed immune reactions are experienced in polytrauma patients, compromising local tissue healing while threatening multiple organ systems. The expanding field of osteoimmunology should contribute to the orthopaedic community's understanding of how the immune system response, whether normal or pathologic, affects the whole body outcome of our patients.

Original languageEnglish
Pages (from-to)297-299
Number of pages3
JournalThe Journal of the American Academy of Orthopaedic Surgeons
Volume29
Issue number7
DOIs
StatePublished - Apr 1 2021

Bibliographical note

Publisher Copyright:
© American Academy of Orthopaedic Surgeons.

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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