Will sexual risk behaviour increase after being vaccinated for AIDS?

Richard A. Crosby, David R. Holtgrave

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The question of whether people will engage in greater levels of HIV-associated risk behaviour after receiving an AIDS vaccine has not been sufficiently investigated. Three objectives were: (1) assess the likelihood that people will engage in greater levels of HIV-risk behaviour after receiving an AIDS vaccine; (2) determine the association of increases with vaccination intent; and (3) identify differences between people who would and would not increase their HIV-risk behaviour after vaccination. A cross-sectional survey was conducted of 278 adults from three populations: gay men, African-American women, and persons who used illicit drugs. Nearly one-quarter of the sample indicated a likelihood that their HIV-risk behaviour would increase after vaccination. This increase was positively associated (r = 0.24) with increased intent to be vaccinated. Previous worry about having HIV (adjusted odds ratio [AOR] = 3.4, P = 0.004), being 32 years of age or older (AOR = 2.9, P = 0.0007), and having less than a high school education (AOR = 2.3, P = 0.027) were each associated with a post-vaccination increase in HIV risk. With the seemingly real potential for increased HIV-risk behaviours after being vaccinated against AIDS, intervention studies are warranted to identify strategies with potential to minimize this phenomenon.

Original languageEnglish
Pages (from-to)180-184
Number of pages5
JournalInternational Journal of STD and AIDS
Issue number3
StatePublished - Mar 2006


  • AIDS vaccine
  • Behaviour
  • HIV
  • Sexual risk

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases


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