Wolbachia re-replacement without incompatibility: Potential for intended and unintended consequences

Philip R. Crain, Philip H. Crowley, Stephen L. Dobson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Recent releases of mosquitoes infected with different Wolbachia types into Australia have led to conditions that have not been observed naturally and that have not been considered theoretically. In an ongoing public health campaign, two Wolbachia infection types have been introduced, and the infections differ in their fitness cost imposed on the host mosquito. The dynamics of each infection type as it interacts with the indigenous uninfected host population have been previously examined via models and empirical tests. Here we conduct a modeling analysis to predict the dynamics when the two infection types do not remain geographically isolated. The results demonstrate the potential replacement and loss of the more costly infection type, which may not be the desired public health outcome.

Original languageEnglish
Pages (from-to)1152-1158
Number of pages7
JournalJournal of Medical Entomology
Issue number5
StatePublished - Sep 2013


  • Aedes aegypti
  • Wolbachia
  • disease control
  • population dynamics
  • population replacement

ASJC Scopus subject areas

  • Parasitology
  • General Veterinary
  • Insect Science
  • Infectious Diseases


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