TY - JOUR
T1 - World association for the advancement of veterinary parasitology (WAAVP)
T2 - Third edition of guideline for evaluating the efficacy of equine anthelmintics
AU - Nielsen, Martin K.
AU - von Samson-Himmelstjerna, Georg
AU - Kuzmina, Tetiana A.
AU - van Doorn, Deborah C.K.
AU - Meana, Aranzazu
AU - Rehbein, Steffen
AU - Elliott, Timothy
AU - Reinemeyer, Craig R.
N1 - Funding Information:
Thomas Geurden is warmly thanked for critically reviewing the manuscript and providing constructive feedback.
Publisher Copyright:
© 2022 The Authors
PY - 2022/3
Y1 - 2022/3
N2 - This guideline have been developed to assist in the design, execution, and interpretation of studies to assess the efficacy of anthelmintic drugs against internal parasites of equines, including nematodes, cestodes, and larval instars of Gasterophilus spp. The design and execution of critical and controlled studies are outlined, and their advantages and disadvantages are discussed. Unique considerations for specific target parasites are included. Information is also provided on selection of animals, procedures for randomization, housing, feeding, dosage titration, dosage confirmation and field studies, record keeping and necropsy procedures. Finally, this document includes guidance for group size determination and statistical analysis of study results. This guideline should assist investigators in the evaluation of anthelmintic drugs in horses by using comparable and standardized procedures in studies with appropriate numbers of animals.
AB - This guideline have been developed to assist in the design, execution, and interpretation of studies to assess the efficacy of anthelmintic drugs against internal parasites of equines, including nematodes, cestodes, and larval instars of Gasterophilus spp. The design and execution of critical and controlled studies are outlined, and their advantages and disadvantages are discussed. Unique considerations for specific target parasites are included. Information is also provided on selection of animals, procedures for randomization, housing, feeding, dosage titration, dosage confirmation and field studies, record keeping and necropsy procedures. Finally, this document includes guidance for group size determination and statistical analysis of study results. This guideline should assist investigators in the evaluation of anthelmintic drugs in horses by using comparable and standardized procedures in studies with appropriate numbers of animals.
KW - Anthelmintics
KW - Controlled test
KW - Critical test
KW - Efficacy
KW - Equine
KW - Gastrointestinal parasites
KW - Guidelines
UR - http://www.scopus.com/inward/record.url?scp=85124524388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85124524388&partnerID=8YFLogxK
U2 - 10.1016/j.vetpar.2022.109676
DO - 10.1016/j.vetpar.2022.109676
M3 - Article
C2 - 35164972
AN - SCOPUS:85124524388
SN - 0304-4017
VL - 303
JO - Veterinary Parasitology
JF - Veterinary Parasitology
M1 - 109676
ER -