Yeast sphingolipid metabolism: Clues and connections

Kellie J. Sims; Stefka D. Spassieva; Eberhard O. Voit; Lina M. Obeid

doi:10.1139/o03-086

Yeast sphingolipid metabolism: Clues and connections

Kellie J. Sims, Stefka D. Spassieva, Eberhard O. Voit, Lina M. Obeid

Physiology

Research output: Contribution to journal › Short survey › peer-review

54 Scopus citations

Abstract

This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.

Original language	English
Pages (from-to)	45-61
Number of pages	17
Journal	Biochemistry and cell biology = Biochimie et biologie cellulaire
Volume	82
Issue number	1
DOIs	https://doi.org/10.1139/o03-086
State	Published - Feb 2004

Keywords

Aging
Protein-protein interactions
Sphingolipid metabolism
Stress response
Subcellular localization
Yeast

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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10.1139/o03-086

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title = "Yeast sphingolipid metabolism: Clues and connections",

abstract = "This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.",

keywords = "Aging, Protein-protein interactions, Sphingolipid metabolism, Stress response, Subcellular localization, Yeast",

author = "Sims, {Kellie J.} and Spassieva, {Stefka D.} and Voit, {Eberhard O.} and Obeid, {Lina M.}",

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AU - Sims, Kellie J.

AU - Spassieva, Stefka D.

AU - Voit, Eberhard O.

AU - Obeid, Lina M.

PY - 2004/2

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N2 - This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.

AB - This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.

KW - Aging

KW - Protein-protein interactions

KW - Sphingolipid metabolism

KW - Stress response

KW - Subcellular localization

KW - Yeast

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SP - 45

EP - 61

IS - 1

ER -

Yeast sphingolipid metabolism: Clues and connections

Abstract

Keywords

ASJC Scopus subject areas

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