TY - JOUR
T1 - Yeast sphingolipid metabolism
T2 - Clues and connections
AU - Sims, Kellie J.
AU - Spassieva, Stefka D.
AU - Voit, Eberhard O.
AU - Obeid, Lina M.
PY - 2004/2
Y1 - 2004/2
N2 - This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.
AB - This review of sphingolipid metabolism in the budding yeast Saccharomyces cerevisiae contains information on the enzymes and the genes that encode them, as well as connections to other metabolic pathways. Particular attention is given to yeast homologs, domains, and motifs in the sequence, cellular localization of enzymes, and possible protein-protein interactions. Also included are genetic interactions of special interest that provide clues to the cellular biological roles of particular sphingolipid metabolic pathways and specific sphingolipids.
KW - Aging
KW - Protein-protein interactions
KW - Sphingolipid metabolism
KW - Stress response
KW - Subcellular localization
KW - Yeast
UR - https://www.scopus.com/pages/publications/2342510923
UR - https://www.scopus.com/inward/citedby.url?scp=2342510923&partnerID=8YFLogxK
U2 - 10.1139/o03-086
DO - 10.1139/o03-086
M3 - Short survey
C2 - 15052327
AN - SCOPUS:2342510923
SN - 0829-8211
VL - 82
SP - 45
EP - 61
JO - Biochemistry and Cell Biology
JF - Biochemistry and Cell Biology
IS - 1
ER -