A novel 100-150-residue domain has been identified in the human splicing factor YT521-B and its Drosophila and yeast homologues. Homology searches show that the domain is typical for the eukaryotes and is particularly abundant in plants. It is predicted to adopt a mixed α-helix-β-sheet fold and to bind to RNA. We propose the name YTH (for YT521-B homology) for the domain.
|Number of pages||3|
|Journal||Trends in Biochemical Sciences|
|State||Published - Oct 1 2002|
ASJC Scopus subject areas
- Molecular Biology