(Z)-2-(1H-Indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one

Vijayakumar N. Sonar; Sean Parkin; Peter A. Crooks

doi:10.1107/S0108270103026076

(Z)-2-(1H-Indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one

Vijayakumar N. Sonar, Sean Parkin, Peter A. Crooks

Chemistry

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The synthesis of 2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octane, (II), from the reductive deoxygenation of the title compound, C ₁₆H₁₆N₂O was discussed. The title compound was prepared by condensation of 1-acetylindole-3-carboxaldehyde under catalysis. Subsequent cleavage of the 1-acetyl group afforded an isomerically pure compound which was identified by Nuclear magnetic resonance (NMR) spectroscopy. The results show that the crystal packing of the title compound involves two types of intermolecular hydrogen bonds.

Original language	English
Pages (from-to)	o6-o8
Journal	Acta Crystallographica Section C: Crystal Structure Communications
Volume	60
Issue number	1
DOIs	https://doi.org/10.1107/S0108270103026076
State	Published - Jan 2004

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Biochemistry, Genetics and Molecular Biology (all)

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title = "(Z)-2-(1H-Indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one",

abstract = "The synthesis of 2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octane, (II), from the reductive deoxygenation of the title compound, C 16H16N2O was discussed. The title compound was prepared by condensation of 1-acetylindole-3-carboxaldehyde under catalysis. Subsequent cleavage of the 1-acetyl group afforded an isomerically pure compound which was identified by Nuclear magnetic resonance (NMR) spectroscopy. The results show that the crystal packing of the title compound involves two types of intermolecular hydrogen bonds.",

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AU - Sonar, Vijayakumar N.

AU - Parkin, Sean

AU - Crooks, Peter A.

PY - 2004/1

Y1 - 2004/1

N2 - The synthesis of 2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octane, (II), from the reductive deoxygenation of the title compound, C 16H16N2O was discussed. The title compound was prepared by condensation of 1-acetylindole-3-carboxaldehyde under catalysis. Subsequent cleavage of the 1-acetyl group afforded an isomerically pure compound which was identified by Nuclear magnetic resonance (NMR) spectroscopy. The results show that the crystal packing of the title compound involves two types of intermolecular hydrogen bonds.

AB - The synthesis of 2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octane, (II), from the reductive deoxygenation of the title compound, C 16H16N2O was discussed. The title compound was prepared by condensation of 1-acetylindole-3-carboxaldehyde under catalysis. Subsequent cleavage of the 1-acetyl group afforded an isomerically pure compound which was identified by Nuclear magnetic resonance (NMR) spectroscopy. The results show that the crystal packing of the title compound involves two types of intermolecular hydrogen bonds.

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(Z)-2-(1H-Indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one

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