The synthesis of 2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octane, (II), from the reductive deoxygenation of the title compound, C 16H16N2O was discussed. The title compound was prepared by condensation of 1-acetylindole-3-carboxaldehyde under catalysis. Subsequent cleavage of the 1-acetyl group afforded an isomerically pure compound which was identified by Nuclear magnetic resonance (NMR) spectroscopy. The results show that the crystal packing of the title compound involves two types of intermolecular hydrogen bonds.
|Journal||Acta Crystallographica Section C: Crystal Structure Communications|
|State||Published - Jan 2004|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology (all)