(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl] benzo-nitrile

Thirupathi Reddy Yerram Reddy; Narsimha Reddy Penthala; Sean Parkin; Peter A. Crooks

doi:10.1107/S1600536808030006

(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl] benzo-nitrile

Thirupathi Reddy Yerram Reddy
, Narsimha Reddy Penthala
, Sean Parkin
, Peter A. Crooks

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The title compound, C24H21N3O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with -bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

Original language	English
Pages (from-to)	o2049
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	64
Issue number	11
DOIs	https://doi.org/10.1107/S1600536808030006
State	Published - 2008

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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title = "(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl] benzo-nitrile",

abstract = "The title compound, C24H21N3O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with -bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50\% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.",

author = "Reddy, \{Thirupathi Reddy Yerram\} and Penthala, \{Narsimha Reddy\} and Sean Parkin and Crooks, \{Peter A.\}",

year = "2008",

doi = "10.1107/S1600536808030006",

language = "English",

volume = "64",

pages = "o2049",

number = "11",

}

TY - JOUR

T1 - (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl] benzo-nitrile

AU - Reddy, Thirupathi Reddy Yerram

AU - Penthala, Narsimha Reddy

AU - Parkin, Sean

AU - Crooks, Peter A.

PY - 2008

Y1 - 2008

N2 - The title compound, C24H21N3O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with -bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

AB - The title compound, C24H21N3O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with -bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

UR - https://www.scopus.com/pages/publications/55749090469

UR - https://www.scopus.com/pages/publications/55749090469#tab=citedBy

U2 - 10.1107/S1600536808030006

DO - 10.1107/S1600536808030006

M3 - Article

C2 - 21580917

AN - SCOPUS:55749090469

SN - 1600-5368

VL - 64

SP - o2049

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 11

ER -

(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl] benzo-nitrile

Abstract

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