(Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl] benzoate

Thirupathi Reddy Yerram Reddy; Narsimha Reddy Penthala; Sean Parkin; Peter A. Crooks

doi:10.1107/S1600536808030018

(Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl] benzoate

Thirupathi Reddy Yerram Reddy, Narsimha Reddy Penthala, Sean Parkin, Peter A. Crooks

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The title compound, C25H24N2O3 was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with methyl p-(bromo-meth-yl)benzoate, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

Original language	English
Pages (from-to)	o2050
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	64
Issue number	11
DOIs	https://doi.org/10.1107/S1600536808030018
State	Published - 2008

ASJC Scopus subject areas

Chemistry (all)
Materials Science (all)
Condensed Matter Physics

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title = "(Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl] benzoate",

abstract = "The title compound, C25H24N2O3 was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with methyl p-(bromo-meth-yl)benzoate, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.",

author = "Reddy, {Thirupathi Reddy Yerram} and Penthala, {Narsimha Reddy} and Sean Parkin and Crooks, {Peter A.}",

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language = "English",

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pages = "o2050",

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T1 - (Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl] benzoate

AU - Reddy, Thirupathi Reddy Yerram

AU - Penthala, Narsimha Reddy

AU - Parkin, Sean

AU - Crooks, Peter A.

PY - 2008

Y1 - 2008

N2 - The title compound, C25H24N2O3 was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with methyl p-(bromo-meth-yl)benzoate, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

AB - The title compound, C25H24N2O3 was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl-ene)-1-aza-bicyclo-[2.2.2]octan-3-one with methyl p-(bromo-meth-yl)benzoate, under phase-transfer catalytic (PTC) conditions using triethyl-benzyl-ammonium chloride and 50% w/v aqueous NaOH solution in dichloro-methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza-bicyclic and indole groups.

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DO - 10.1107/S1600536808030018

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VL - 64

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ER -

(Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl] benzoate

Abstract

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