Perfil personal
Research Interests
The Schock lab uses Xenopus (frog) and mice to study embryonic development. We are specifically interested in the developing face and the cells that contribute to much of the facial architecture, the neural crest. Research in the lab is centered around two central questions.
1) We are intrested in undestanding how neural crest cells make cell fate decisions, with a current interest in the role of Sox transcription factors in this process.
2) We aim to develop and study disease model for human craniofacial syndromes, with a specific interest in patient-specific variants.
Cuantificación de educación / académica
Developmental Biology, Postdoc, Northwestern University
ago 2017 → ago 2024
Doctor of Philosophy, Cincinnati Children's Hospital Medical Center
2017
Master of Science, Wittenberg University
2012
Keywords
- QH301 Biology
- QH426 Genetics
- QM Human anatomy
Experiencia relacionada con los ODS de las Naciones Unidas
En 2015, los estados miembros de las Naciones Unidas acordaron 17 Objetivos de Desarrollo Sostenible (ODS) para erradicar la pobreza, proteger el planeta y garantizar la prosperidad para todos. El trabajo de esta persona contribuye al logro de los siguientes ODS:
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Good health and well being
Huella digital
- 1 Perfiles similares
Colaboraciones y áreas de investigación principales de los últimos cinco años
Proyectos
- 2 Activo
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Elucidating the Etiology for Schneckenbecken Dysplasia, a Rare Disease, Using a Vetrebrate Model System
Schock, B. (PI) & Huber, P. (CoI)
National Institute of Dental and Craniofacial Research
3/1/26 → 2/28/27
Proyecto: Research project
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The Role of SoxE Transcription Factors in Neural Crest Cell Specialization
Schock, B. (PI)
National Institute of Dental and Craniofacial Research
9/16/24 → 8/31/27
Proyecto: Research project
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Shared features of blastula and neural crest stem cells evolved at the base of vertebrates
York, J. R., Rao, A., Huber, P. B., Schock, E. N., Montequin, A., Rigney, S. & LaBonne, C., sept 2024, En: Nature Ecology and Evolution. 8, 9, p. 1680-1692 13 p.Producción científica: Article › revisión exhaustiva
Acceso abierto11 Citas (Scopus) -
SoxB1 transcription factors are essential for initiating and maintaining neural plate border gene expression
Schock, E. N., York, J. R., Li, A. P., Tu, A. Y. & LaBonne, C., jul 2024, En: Development (Cambridge). 151, 14Producción científica: Article › revisión exhaustiva
Acceso abierto4 Citas (Scopus) -
Corrigendum to “A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells” [Dev Biol. 2018 Dec 15 444(2):50–61] (Developmental Biology (2018) 444(2) (50–61), (S0012160618302598), (10.1016/j.ydbio.2018.08.008))
Buitrago-Delgado, E., Schock, E. N., Nordin, K. & LaBonne, C., ene 2023, En: Developmental Biology. 493, p. 12 1 p.Producción científica: Comment/debate
Acceso abierto -
Production and characterization of monoclonal antibodies to Xenopus proteins
Horr, B., Kurtz, R., Pandey, A., Hoffstrom, B. G., Schock, E., LaBonne, C. & Alfandari, D., feb 2023, En: Development (Cambridge). 150, 4, dev201309.Producción científica: Article › revisión exhaustiva
Acceso abierto7 Citas (Scopus) -
The developmental and evolutionary origins of cellular pluripotency in the vertebrate neural crest
Schock, E. N., York, J. R. & LaBonne, C., mar 30 2023, En: Seminars in Cell and Developmental Biology. 138, p. 36-44 9 p.Producción científica: Review article › revisión exhaustiva
Acceso abierto17 Citas (Scopus)