!!Projects per year
Perfil personal
Research Interests
Abl non-receptor tyrosine kinases, cancer invasion.
Cuantificación de educación / académica
Doctor of Philosophy, Indiana University
1992
Bachelor of Arts, Colorado College
1985
Experiencia relacionada con los ODS de las Naciones Unidas
En 2015, los estados miembros de las Naciones Unidas acordaron 17 Objetivos de Desarrollo Sostenible (ODS) para erradicar la pobreza, proteger el planeta y garantizar la prosperidad para todos. El trabajo de esta persona contribuye al logro de los siguientes ODS:
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Good health and well being
Huella digital
- 1 Perfiles similares
Colaboraciones y áreas de investigación principales de los últimos cinco años
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FY27 ABL and Pediatric Glioma
Plattner, R. (PI), Lightner, D. (CoI), Munnikhuysen, S. (CoI), Neltner, J. (CoI), Thibault, O. (CoI) & Wang, C. (CoI)
KY Cabinet for Health and Family Services
7/1/26 → 6/30/28
Proyecto: Research project
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CCSG Pilot: Uncovering Signaling Pathways Driving High Melanoma Mortality in Rural Kentucky
Plattner, R. (PI), Arays, R. (CoI), Huang, B. (CoI), Richards, D. (CoI), Stapleton, J. (CoI) & Wang, C. (CoI)
7/1/25 → 6/30/27
Proyecto: Research project
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Targeting ABL1/2 And DDR1 Tyrosine Kinases for Treating NRAS-Mutant Melanoma
Plattner, R. (PI), Arays, R. (CoI), Liu, J. (CoI), Richards, D. (CoI) & Wang, C. (CoI)
6/1/25 → 6/1/29
Proyecto: Research project
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Combating Melanoma Resistance by Targeting ABL1/2
Plattner, R. (PI), Arays, R. (CoI), Gandhapudi, S. (CoI), Liu, J. (CoI), Richards, D. (CoI), Wang, C. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Kolesar, J. (Former CoPI), COHEN, D. (Former CoI) & Wang, P. (Former CoI)
5/23/22 → 4/30/27
Proyecto: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Community Outreach and Engagement (COE))
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. M. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)
7/8/13 → 6/30/28
Proyecto: Research project
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ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization
Lyon, A., Tripathi, R., Meeks, C., He, D., Wu, Y., Liu, J., Wang, C., Chen, J., Zhu, H., Mukherjee, S., Ganguly, S. & Plattner, R., feb 2023, En: Cancers. 15, 3, 954.Producción científica: Article › revisión exhaustiva
Acceso abierto3 Citas (Scopus) -
Inhibition of ABL1 by tyrosine kinase inhibitors leads to a downregulation of MLH1 by Hsp70-mediated lysosomal protein degradation
Daniels, H. G., Knicely, B. G., Miller, A. K., Thompson, A., Plattner, R. & Goellner, E. M., oct 20 2022, En: Frontiers in Genetics. 13, 940073.Producción científica: Article › revisión exhaustiva
Acceso abierto1 Cita (Scopus) -
Keap1 is required for artesunate anticancer activity in non-small-cell lung cancer
Hill, K. S., McDowell, A., McCorkle, J. R., Schuler, E., Ellingson, S. R., Plattner, R. & Kolesar, J. M., abr 2 2021, En: Cancers. 13, 8, 1885.Producción científica: Article › revisión exhaustiva
Acceso abierto22 Citas (Scopus) -
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling
Tripathi, R., Liu, Z., Jain, A., Lyon, A., Meeks, C., Richards, D., Liu, J., He, D., Wang, C., Nespi, M., Rymar, A., Wang, P., Wilson, M. & Plattner, R., dic 1 2020, En: Nature Communications. 11, 1, 5463.Producción científica: Article › revisión exhaustiva
Acceso abierto42 Citas (Scopus) -
Potential protein markers for breast cancer recurrence: a retrospective cohort study
He, C., Plattner, R., Rangnekar, V., Zhou, B., Liu, C., Stewart, R. L., Huang, B., Wang, C. & Tucker, T. C., ene 1 2019, En: Cancer Causes and Control. 30, 1, p. 41-51 11 p.Producción científica: Article › revisión exhaustiva
5 Citas (Scopus)