Cancer Prevention and Control: An Integrated, Population-Based Community and Cancer Center Program, A Focus on Early Detection, Molecular Epidemiology and State-of-the-Art Treatment for Lung, Esophageal, Liver and Pancreatic Cancer

The long-term goal of this translational research project is to develop a vibrant fully integrated cancer center & community program that concentrates on reducing the morbidity and mortality of lung, esophageal, liver, and pancreatic cancers. The dominant theme is a focused early detection/screening strategy. To reach this goal, the project, of necessity, has two related yet discrete arms. One arm supports prevention, amelioration of nicotine dependence, and early detection strategies in a populationbased approach. The second arm employs evidence-based methods to diagnose, optimally treat, manage symptoms, and deliver palliative care. Both arms provide a strong platform for translational research where application of bench science evolves quickly into clinical science. These approaches include the integration of molecular epidemiology.