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A genome-wide affected sibpair linkage analysis of hypertension: The HyperGEN Network

  • Dabeeru C. Rao
  • , Michael A. Province
  • , Mark F. Leppert
  • , Al Oberman
  • , Gerardo Heiss
  • , R. Curt Ellison
  • , Donna K. Arnett
  • , John H. Eckfeldt
  • , Karen Schwander
  • , Steve C. Mockrin
  • , Steve C. Hunt

Producción científica: Articlerevisión exhaustiva

63 Citas (Scopus)

Resumen

Results are reported here from a genome-wide linkage analysis of hypertension in a large sample of hypertensive (affected) sibpairs (650 African American and 915 white sibpairs) recruited by the HyperGEN Network of the National Heart, Lung and Blood Institute (NHLBI) Family Blood Pressure Program (FBPP). Analysis using MAPMAKER/SIBS suggests one interesting region with a LOD score of 2.08 at 63 cM from the p telomere on chromosome 2 in the African American sibpairs, which may harbor hypertension susceptibility genes.

Idioma originalEnglish
Páginas (desde-hasta)148-150
Número de páginas3
PublicaciónAmerican Journal of Hypertension
Volumen16
N.º2
DOI
EstadoPublished - feb 1 2003

Financiación

FinanciadoresNúmero del financiador
National Heart, Lung, and Blood Institute (NHLBI)U10HL054497

    ASJC Scopus subject areas

    • Internal Medicine

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