A not-so-simple twist of fate

Alexandra F. Long; Tim Stearns

doi:10.1016/j.devcel.2021.02.003

A not-so-simple twist of fate

Alexandra F. Long
, Tim Stearns

Biology

Producción científica: Article › revisión exhaustiva

2 Citas (Scopus)

Resumen

Multiciliated cells are considered terminally differentiated, yet tissues bearing them are remodeled during development and after injury. In this issue of Developmental Cell, Tasca et al. (2021) show that multiciliated epithelial cells are lost via two different Notch-dependent processes, apoptosis and transdifferentiation, during developmental remodeling of the Xenopus epidermis.Multiciliated cells are considered terminally differentiated, yet tissues bearing them are remodeled during development and after injury. In this issue of Developmental Cell, Tasca et al. (2021) show that multiciliated epithelial cells are lost via two different Notch-dependent processes, apoptosis and transdifferentiation, during developmental remodeling of the Xenopus epidermis.

Idioma original	English
Páginas (desde-hasta)	402-404
Número de páginas	3
Publicación	Developmental Cell
Volumen	56
N.º	4
DOI	https://doi.org/10.1016/j.devcel.2021.02.003
Estado	Published - feb 22 2021

Nota bibliográfica

Publisher Copyright:
© 2021 Elsevier Inc.

Financiación

Financiadores	Número del financiador
National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences	R35GM130286
National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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AB - Multiciliated cells are considered terminally differentiated, yet tissues bearing them are remodeled during development and after injury. In this issue of Developmental Cell, Tasca et al. (2021) show that multiciliated epithelial cells are lost via two different Notch-dependent processes, apoptosis and transdifferentiation, during developmental remodeling of the Xenopus epidermis.Multiciliated cells are considered terminally differentiated, yet tissues bearing them are remodeled during development and after injury. In this issue of Developmental Cell, Tasca et al. (2021) show that multiciliated epithelial cells are lost via two different Notch-dependent processes, apoptosis and transdifferentiation, during developmental remodeling of the Xenopus epidermis.

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JO - Developmental Cell

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A not-so-simple twist of fate

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

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