A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks

Jiajie Peng; Hongxiang Li; Yadong Wang; Jin Chen

doi:10.1145/2808719.2816835

A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks

Jiajie Peng, Hongxiang Li, Yadong Wang, Jin Chen

Internal Medicine

Producción científica: Conference contribution › revisión exhaustiva

Resumen

Gene Ontology(GO) is one of the most popular bioinformatic resource to study functional relationships between genes. However, the existing tools for calculating the semantic similarity are limited since they only rely on GO annotations and structure. We provide a working demonstration of a web tool that calculates functional similarities between GO terms by integrating gene co-function networks and information from GO. We demonstrate the function of the web tool by comparing remote GO terms. Copyright is held by the author/owner(s).

Idioma original	English
Título de la publicación alojada	BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics
Páginas	678-679
Número de páginas	2
ISBN (versión digital)	9781450338530
DOI	https://doi.org/10.1145/2808719.2816835
Estado	Published - sept 9 2015
Evento	6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015 - Atlanta, United States Duración: sept 9 2015 → sept 12 2015

Serie de la publicación

Nombre	BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics

Conference

Conference	6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015
País/Territorio	United States
Ciudad	Atlanta
Período	9/9/15 → 9/12/15

Nota bibliográfica

Publisher Copyright:
Copyright is held by the author/owner(s).

ASJC Scopus subject areas

Software
Health Informatics
Computer Science Applications
Biomedical Engineering

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10.1145/2808719.2816835

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Peng, J., Li, H., Wang, Y., & Chen, J. (2015). A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks. En BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (pp. 678-679). (BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics). https://doi.org/10.1145/2808719.2816835

Peng, Jiajie ; Li, Hongxiang ; Wang, Yadong et al. / A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks. BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. 2015. pp. 678-679 (BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics).

@inproceedings{1084b2696a9243eebf367bc1668517ae,

title = "A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks",

abstract = "Gene Ontology(GO) is one of the most popular bioinformatic resource to study functional relationships between genes. However, the existing tools for calculating the semantic similarity are limited since they only rely on GO annotations and structure. We provide a working demonstration of a web tool that calculates functional similarities between GO terms by integrating gene co-function networks and information from GO. We demonstrate the function of the web tool by comparing remote GO terms. Copyright is held by the author/owner(s).",

keywords = "Gene ontology, Semantic similarity, Software tools",

author = "Jiajie Peng and Hongxiang Li and Yadong Wang and Jin Chen",

note = "Publisher Copyright: Copyright is held by the author/owner(s).; 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015 ; Conference date: 09-09-2015 Through 12-09-2015",

year = "2015",

month = sep,

day = "9",

doi = "10.1145/2808719.2816835",

language = "English",

series = "BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics",

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Peng, J, Li, H, Wang, Y & Chen, J 2015, A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks. En BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, pp. 678-679, 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015, Atlanta, United States, 9/9/15. https://doi.org/10.1145/2808719.2816835

A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks. / Peng, Jiajie; Li, Hongxiang; Wang, Yadong et al.
BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. 2015. p. 678-679 (BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics).

Producción científica: Conference contribution › revisión exhaustiva

TY - GEN

T1 - A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks

AU - Peng, Jiajie

AU - Li, Hongxiang

AU - Wang, Yadong

AU - Chen, Jin

N1 - Publisher Copyright: Copyright is held by the author/owner(s).

PY - 2015/9/9

Y1 - 2015/9/9

N2 - Gene Ontology(GO) is one of the most popular bioinformatic resource to study functional relationships between genes. However, the existing tools for calculating the semantic similarity are limited since they only rely on GO annotations and structure. We provide a working demonstration of a web tool that calculates functional similarities between GO terms by integrating gene co-function networks and information from GO. We demonstrate the function of the web tool by comparing remote GO terms. Copyright is held by the author/owner(s).

AB - Gene Ontology(GO) is one of the most popular bioinformatic resource to study functional relationships between genes. However, the existing tools for calculating the semantic similarity are limited since they only rely on GO annotations and structure. We provide a working demonstration of a web tool that calculates functional similarities between GO terms by integrating gene co-function networks and information from GO. We demonstrate the function of the web tool by comparing remote GO terms. Copyright is held by the author/owner(s).

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KW - Semantic similarity

KW - Software tools

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M3 - Conference contribution

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BT - BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics

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Peng J, Li H, Wang Y, Chen J. A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks. En BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. 2015. p. 678-679. (BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics). doi: 10.1145/2808719.2816835

A web tool for measuring gene semantic similarities by combining gene ontology and gene co-function networks

Resumen

Serie de la publicación

Conference

Nota bibliográfica

ASJC Scopus subject areas

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