TY - JOUR
T1 - Aerosolized tacrolimus
T2 - A case report in a lung transplant recipient
AU - Hayes, D.
AU - Zwischenberger, J. B.
AU - Mansour, H. M.
PY - 2010/11
Y1 - 2010/11
N2 - Long-term outcomes after lung transplantation remain poor mainly to the development of bronchiolitis obliterans syndrome (BOS). Currently, treatment options for BOS are very limited. Strategies to prevent and treat this complication include the use of aerosolized therapy with only cyclosporine used in patients to date. We describe the use of aerosolized tacrolimus in a lung transplant recipient with BOS. The patient demonstrated clinical improvement in functional capacity and oxygenation while receiving tacrolimus by nebulization. Further research is needed to study whether aerosolized tacrolimus is beneficial in lung transplant recipients with BOS.
AB - Long-term outcomes after lung transplantation remain poor mainly to the development of bronchiolitis obliterans syndrome (BOS). Currently, treatment options for BOS are very limited. Strategies to prevent and treat this complication include the use of aerosolized therapy with only cyclosporine used in patients to date. We describe the use of aerosolized tacrolimus in a lung transplant recipient with BOS. The patient demonstrated clinical improvement in functional capacity and oxygenation while receiving tacrolimus by nebulization. Further research is needed to study whether aerosolized tacrolimus is beneficial in lung transplant recipients with BOS.
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U2 - 10.1016/j.transproceed.2010.08.029
DO - 10.1016/j.transproceed.2010.08.029
M3 - Article
C2 - 21094875
AN - SCOPUS:78649455044
SN - 0041-1345
VL - 42
SP - 3876
EP - 3879
JO - Transplantation Proceedings
JF - Transplantation Proceedings
IS - 9
ER -