Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Anchorage Independent Growth 100%
• Kinase 50%
• Phosphotransferase 50%
• RNA Interference 25%
• Cell Proliferation 25%
• STAT3 25%
• Cell Cycle Progression 25%
• Cell Anchorage 25%
• Epidermal Growth Factor Receptor 25%
• Protein Kinase C 25%
• Arginine 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Breast Cancer 100%
• Abelson Kinase 100%
• Leukemia 8%
• Phosphotransferase Inhibitor 8%
• Solid Malignant Neoplasm 8%
• Arginine 8%
• Epidermal Growth Factor Receptor 8%
• Protein Kinase C 8%