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Available space and extracellular transport of macromolecules: Effects of pore size and connectedness

Producción científica: Articlerevisión exhaustiva

51 Citas (Scopus)

Resumen

Available space and extracellular transport of macromolecules was described. Volume fraction of dextran was found to decrease sharply in tumor tissues when the molecular weight (MW) was increased from 40,000 to 70,000. Numerical simulations revealed that the sharp decrease in volume fraction of solutes required the existence of at least two populations of pores and the lack of connectedness of available pores in the interstitial space.

Idioma originalEnglish
Páginas (desde-hasta)1150-1158
Número de páginas9
PublicaciónAnnals of Biomedical Engineering
Volumen29
N.º12
DOI
EstadoPublished - 2001

Nota bibliográfica

Funding Information:
The work is supported by a grant from the Whitaker Foundation (97-0062).

Financiación

The work is supported by a grant from the Whitaker Foundation (97-0062).

FinanciadoresNúmero del financiador
The Whitaker Foundation97-0062
The Whitaker Foundation

    ASJC Scopus subject areas

    • Biomedical Engineering

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