Resumen
PurposeThis research investigates whether the efficacy of a digital cannabis use disorder (CUD) treatment for young adults (age 18–25) differs by exposure to cannabis retailers in the residential neighborhood and activity space (significant places visited throughout daily life).MethodsThis is a secondary analysis of data from a randomized clinical trial of the digital substance use disorder treatment Peer Network Counseling-txt (PNC-txt) for reducing cannabis use among young adults with CUD (n = 425). We hypothesize that the indirect effect of treatment on reducing cannabis use via the mediating mechanism readiness-to-change is moderated by exposure to cannabis retailers, due to the stronger effect of readiness-to-change on reducing cannabis use at lower levels of exposure.ResultsThe indirect effect of PNC-txt on reducing cannabis use is significantly moderated by activity space exposure to cannabis retailers (β=0.104, 95 % CI: 0.010, 0.197), where the treatment effect is more than three times as strong at low, as compared to high, levels of exposure. We did not find significant moderating effects by residential exposure (β=0.059, 95 % CI: −0.020, 0.137).ConclusionsFindings indicate that greater exposure to cannabis retailers in a young adult’s activity space is associated with reduced CUD treatment efficacy. This is likely due to easier access to cannabis, more tolerant cannabis attitudes, and environmental cues which can trigger craving among those with CUD. Regulations regarding locations and density of cannabis retailers may contribute to better CUD treatment outcomes.
| Idioma original | English |
|---|---|
| Número de artículo | 113096 |
| Publicación | Drug and Alcohol Dependence |
| Volumen | 282 |
| DOI | |
| Estado | Published - may 1 2026 |
Nota bibliográfica
Publisher Copyright:© 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
Financiación
Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under Award Number 5R01DA044206 (PIs M.J. Mason and J.D. Coatsworth) and by the National Science Foundation under Award Number 2445784 (PI J. Mennis). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or National Science Foundation. Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under Award Number 5R01DA044206 (PIs M.J. Mason and J.D. Coatsworth) and by the National Science Foundation under Award Number 2445784 (PI J. Mennis). Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under Award Number 5R01DA044206 (PIs M.J. Mason and J.D. Coatsworth) and by the National Science Foundation under Award Number 2445784 (PI J. Mennis).
| Financiadores | Número del financiador |
|---|---|
| Author National Institute on Drug Abuse DA031791 Mark J Ferris National Institute on Drug Abuse DA006634 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA026117 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA028162 Elizabeth G Pitts National Institute of General Medical Sciences GM102773 Elizabeth G Pitts Peter McManus Charitable Trust Mark J Ferris National Institute on Drug Abuse | |
| National Institutes of Health (NIH) | 5R01DA044206 |
| National Science Foundation Arctic Social Science Program | 2445784 |
ODS de las Naciones Unidas
Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible
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Good health and well being
ASJC Scopus subject areas
- Toxicology
- Pharmacology
- Psychiatry and Mental health
- Pharmacology (medical)
Huella
Profundice en los temas de investigación de 'Cannabis retail environment and treatment for cannabis use disorder'. En conjunto forman una huella única.Citar esto
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