Case report: Acyclovir neurotoxicity and nephrotoxicity - The role for hemodialysis

B. F. Krieble; D. W. Rudy; M. R. Glick; M. D. Clayman

doi:10.1097/00000441-199301000-00007

Case report: Acyclovir neurotoxicity and nephrotoxicity - The role for hemodialysis

B. F. Krieble
, D. W. Rudy
, M. R. Glick
, M. D. Clayman

Producción científica: Article › revisión exhaustiva

58 Citas (Scopus)

Resumen

Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was associated with a reduction in plasma acyclovir concentration. Acute hemodialysis therapy should be considered in cases of serious neurotoxicity secondary to acyclovir, especially when accompanied by renal failure.

Idioma original	English
Páginas (desde-hasta)	36-39
Número de páginas	4
Publicación	American Journal of the Medical Sciences
Volumen	305
N.º	1
DOI	https://doi.org/10.1097/00000441-199301000-00007
Estado	Published - 1993

Nota bibliográfica

Funding Information:
From Wishard Memorial Hospital, Indiana University School of Medicine, Indianapolis, Indiana. Dr. Rudy is a recipient of a Pharmaceutical Manufacturers Association Foundation Fellowship Award for clinical pharmacology. Correspondence: Barry F. Krieble, MD, Nephrology Section, Indiana University School of Medicine, Fesler Hall, Room 108, 1120 South Drive, Indianapolis, IN 46202-5116.

Financiación

From Wishard Memorial Hospital, Indiana University School of Medicine, Indianapolis, Indiana. Dr. Rudy is a recipient of a Pharmaceutical Manufacturers Association Foundation Fellowship Award for clinical pharmacology. Correspondence: Barry F. Krieble, MD, Nephrology Section, Indiana University School of Medicine, Fesler Hall, Room 108, 1120 South Drive, Indianapolis, IN 46202-5116.

Financiadores
Pharmaceutical Manufacturers Association Foundation

ODS de las Naciones Unidas

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Good health and well being

ASJC Scopus subject areas

General Medicine

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abstract = "Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was associated with a reduction in plasma acyclovir concentration. Acute hemodialysis therapy should be considered in cases of serious neurotoxicity secondary to acyclovir, especially when accompanied by renal failure.",

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Case report: Acyclovir neurotoxicity and nephrotoxicity - The role for hemodialysis

Resumen

Nota bibliográfica

Financiación

ODS de las Naciones Unidas

ASJC Scopus subject areas

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