Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

Christopher M. Waters; Ushma Savla; Pam Kuagoolwongse; Peter H.S. Sporn

Cellular mechanics in human blood eosinophils and leukotriene C ₄ synthesis

Christopher M. Waters
, Ushma Savla
, Pam Kuagoolwongse
, Peter H.S. Sporn

Physiology

Producción científica: Conference article › revisión exhaustiva

Resumen

Cellular mechanics in human blood eosinophils and leukotriene C ₄ (LTC₄) synthesis were studied. The inhibition of LTC₄ synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC₄ synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

Idioma original	English
Páginas (desde-hasta)	635-636
Número de páginas	2
Publicación	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volumen	50
Estado	Published - 2001
Evento	Proceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States Duración: jun 27 2001 → jul 1 2001

ASJC Scopus subject areas

General Engineering

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title = "Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis",

abstract = "Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.",

author = "Waters, \{Christopher M.\} and Ushma Savla and Pam Kuagoolwongse and Sporn, \{Peter H.S.\}",

year = "2001",

language = "English",

volume = "50",

pages = "635--636",

note = "Proceedings of the 2001 Bioengineering Conference ; Conference date: 27-06-2001 Through 01-07-2001",

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TY - JOUR

T1 - Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

AU - Waters, Christopher M.

AU - Savla, Ushma

AU - Kuagoolwongse, Pam

AU - Sporn, Peter H.S.

PY - 2001

Y1 - 2001

N2 - Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

AB - Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

UR - https://www.scopus.com/pages/publications/0242525104

UR - https://www.scopus.com/pages/publications/0242525104#tab=citedBy

M3 - Conference article

AN - SCOPUS:0242525104

SN - 1071-6947

VL - 50

SP - 635

EP - 636

JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

JF - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

T2 - Proceedings of the 2001 Bioengineering Conference

Y2 - 27 June 2001 through 1 July 2001