Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety

María L. De La Puente; Robert B. Grossman; Steven V. Ley; Monique S.J. Simmonds; Wally M. Blaney

doi:10.1039/p19960001517

Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety

María L. De La Puente
, Robert B. Grossman
, Steven V. Ley
, Monique S.J. Simmonds
, Wally M. Blaney

Chemistry

Producción científica: Article › revisión exhaustiva

9 Citas (Scopus)

Resumen

A synthetic route to mimics of the insect antifeedant azadirachtin 1 containing the hydroxytetrahydrofurancarboxylate hemiketal functional moiety has been developed. Two of these compounds, 2 and 11, show significant antifeedant activity against Spodoptera littoralis, although they are not as active as azadirachtin.

Idioma original	English
Páginas (desde-hasta)	1517-1521
Número de páginas	5
Publicación	Journal of the Chemical Society - Perkin Transactions 1
N.º	13
DOI	https://doi.org/10.1039/p19960001517
Estado	Published - jul 7 1996

ASJC Scopus subject areas

General Chemistry

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10.1039/p19960001517

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De La Puente, M. L., Grossman, R. B., Ley, S. V., Simmonds, M. S. J., & Blaney, W. M. (1996). Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety. Journal of the Chemical Society - Perkin Transactions 1, (13), 1517-1521. https://doi.org/10.1039/p19960001517

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abstract = "A synthetic route to mimics of the insect antifeedant azadirachtin 1 containing the hydroxytetrahydrofurancarboxylate hemiketal functional moiety has been developed. Two of these compounds, 2 and 11, show significant antifeedant activity against Spodoptera littoralis, although they are not as active as azadirachtin.",

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De La Puente, ML, Grossman, RB, Ley, SV, Simmonds, MSJ & Blaney, WM 1996, 'Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety', Journal of the Chemical Society - Perkin Transactions 1, n.º 13, pp. 1517-1521. https://doi.org/10.1039/p19960001517

Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety. / De La Puente, María L.; Grossman, Robert B.; Ley, Steven V. et al.
En: Journal of the Chemical Society - Perkin Transactions 1, N.º 13, 07.07.1996, p. 1517-1521.

Producción científica: Article › revisión exhaustiva

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De La Puente ML, Grossman RB, Ley SV, Simmonds MSJ, Blaney WM. Chemistry of insect antifeedants from Azadirachta indica (Part 20): Synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety. Journal of the Chemical Society - Perkin Transactions 1. 1996 jul 7;(13):1517-1521. doi: 10.1039/p19960001517