TY - JOUR
T1 - Comparison of the Host Ranges and Antigenicity of Cryptosporidium parvum and Cryptosporidium wrairi from Guinea Pigs
AU - CHRISP, CLARENCE E.
AU - SUCKOW, MARK A.
AU - FAYER, RONALD
AU - ARROWOOD, MICHAEL J.
AU - HEALEY, MARK C.
AU - STERLING, CHARLES R.
PY - 1992/5
Y1 - 1992/5
N2 - ABSTRACT. Oocysts of a Cryptosporidium isolate from guinea pigs were not infectious for adult mice, but were infectious for two of three newborn calves and for suckling mice. However, oocysts isolated from calves or mice infected with guinea pig Cryptosporidium were not infectious for guinea pigs. Four isolates of C. parvum from calves were incapable of infecting weanling guinea pigs. Microscopic examination of tissue from the colon and cecum of suckling guinea pigs inoculated with C. parvum revealed sparse infection of some pups. These host range studies and previously described differences in 125I‐labeled oocyst surface protein profiles between Cryptosporidium sp. from guinea pigs and C. parvum suggest they are distinct species. We propose the name Cryptosporidium wrairi be retained. Studies with monoclonal antibodies indicate that C. wrairi and C. parvum are antigenically related.
AB - ABSTRACT. Oocysts of a Cryptosporidium isolate from guinea pigs were not infectious for adult mice, but were infectious for two of three newborn calves and for suckling mice. However, oocysts isolated from calves or mice infected with guinea pig Cryptosporidium were not infectious for guinea pigs. Four isolates of C. parvum from calves were incapable of infecting weanling guinea pigs. Microscopic examination of tissue from the colon and cecum of suckling guinea pigs inoculated with C. parvum revealed sparse infection of some pups. These host range studies and previously described differences in 125I‐labeled oocyst surface protein profiles between Cryptosporidium sp. from guinea pigs and C. parvum suggest they are distinct species. We propose the name Cryptosporidium wrairi be retained. Studies with monoclonal antibodies indicate that C. wrairi and C. parvum are antigenically related.
KW - Monoclonal antibodies
KW - oocysts
KW - sporozoites
KW - transmission experiments
UR - https://www.scopus.com/pages/publications/0026861003
UR - https://www.scopus.com/pages/publications/0026861003#tab=citedBy
U2 - 10.1111/j.1550-7408.1992.tb01471.x
DO - 10.1111/j.1550-7408.1992.tb01471.x
M3 - Article
C2 - 1386385
AN - SCOPUS:0026861003
SN - 0022-3921
VL - 39
SP - 406
EP - 409
JO - Journal of Eukaryotic Microbiology
JF - Journal of Eukaryotic Microbiology
IS - 3
ER -