Constructs of the Stress–Appraisal–Coping Theory and Positive Human Traits as Predictors of Perceived Stress in People With Multiple Sclerosis: Implications for Rehabilitation Professions

People with multiple sclerosis (MS) often have to cope with high levels of stress. Lazarus and Folkman’s (1984) stress–appraisal–coping theory emphasizes the relationship between the individual and the environment, suggesting that a stress response is highly influenced by individual appraisal processes. This study aimed to evaluate constructs of Lazarus and Folkman’s stress–appraisal–coping theory and positive human traits as predictors of perceived stress in a sample of 477 adults with MS. Hierarchical regression analysis was used to determine the incremental variance in perceived stress accounted for by demographic covariates, functional disabilities, challenge appraisal, and positive human traits. Core self-evaluations, challenge appraisal, limitations in social/cognitive functioning, agency hope, and age were significant predictors in the final model, accounting for 68% of the variance in perceived stress scores (R2 = .68, f2 = 2.13; large effect size). Core self-evaluations and challenge appraisal were the strongest predictors of perceived stress. The findings from this study will help rehabilitation professionals develop empirically supported stress management and well-being interventions, enabling people with MS to cope effectively with stressors and challenges and improve their health and well-being.