Contribution of previable births to infant mortality rate racial disparity in the United States

MacKenzie K. Lee; Eric S. Hall; Emily DeFranco

doi:10.1038/s41372-019-0394-x

Contribution of previable births to infant mortality rate racial disparity in the United States

MacKenzie K. Lee
, Eric S. Hall
, Emily DeFranco

Obstetrics and Gynecology

Producción científica: Article › revisión exhaustiva

3 Citas (Scopus)

Resumen

Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1%, 7.7%, and 5.0% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.

Idioma original	English
Páginas (desde-hasta)	1190-1195
Número de páginas	6
Publicación	Journal of Perinatology
Volumen	39
N.º	9
DOI	https://doi.org/10.1038/s41372-019-0394-x
Estado	Published - sept 1 2019

Nota bibliográfica

Publisher Copyright:
© 2019, Springer Nature America, Inc.

Financiación

Funding ML received research funding from an educational grant from the University of Cincinnati, Department of Obstetrics and Gynecology Women’s Health Scholars Program at the University of Cincinnati College of Medicine. ED received research funding from the Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; March of Dimes Prematurity Research Center Ohio Collaborative

Financiadores	Número del financiador
Department of Obstetrics and Gynecology Women’s Health Scholars Program
Perinatal Institute
March of Dimes Research Foundation	22-FY14-470
Cincinnati Children's Hospital Medical Center
University of Cincinnati University Research Council
March of Dimes Prematurity Research Center Ohio Collaborative
University of Cincinnati College of Medicine

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1038/s41372-019-0394-x

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abstract = "Objective: To quantify racial differences in contribution of previable live births (<20 weeks gestational age (GA)) to United States (US) Infant Mortality Rates (IMR). Methods: Population-based retrospective cohort of US live births (2007–14) using CDC WONDER database stratified by maternal race/ethnicity. We compared the contribution of previable births to IMR and calculated modified IMRs (≥20 weeks GA) excluding previable live births in each group. Contingency tables and chi-square calculations were performed to detect differences between groups. Results: Previable deaths represented 4.1\%, 7.7\%, and 5.0\% of total deaths for nonHispanic white, nonHispanic black, and Hispanic, respectively. Previable contribution to total IMR are 0.21, 0.89, and 0.26 per 1000 live births (P < 0.0001). Modified IMRs are 4.98, 10.85, and 4.69 deaths per 1000 live births. Conclusion: IMR standardization with a minimum GA may obscure the disproportionate contribution of previable births to IMRs among the black population, which has the largest proportion of previable births.",

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Contribution of previable births to infant mortality rate racial disparity in the United States

Resumen

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Financiación

ODS de las Naciones Unidas

ASJC Scopus subject areas

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