Resumen
The authors regret that we inadvertently did not list the authors with PIKASO Team corporate authorship. These authors have now been appropriately included. The authors would like to apologise for any inconvenience caused.
| Idioma original | English |
|---|---|
| Número de artículo | 100665 |
| Publicación | Osteoarthritis and Cartilage Open |
| Volumen | 7 |
| N.º | 4 |
| DOI |
|
| Estado | Published - dic 2025 |
Nota bibliográfica
Publisher Copyright:© 2025 The Author(s)
Financiación
Supported by the Arthritis Foundation Osteoarthritis Clinical Trial Network. The PIKASO trial is led by two co-Principal Investigators, an orthopedic sports medicine surgeon (MHJ) and a clinical orthopaedic researcher (CAJ). They are advised by the Arthritis Foundation's Osteoarthritis Clinical Trials Network (OA-CTN) Steering Committee, which includes clinician-scientists, biostatisticians, and laboratory scientists, as well as several core coordinating centers (led by DTF). The Data Coordinating Center (DCC) at Mass General Brigham (led by EL and JC) oversees day-to-day operations of the trial, including monitoring screening and recruitment, randomization, organizing staff training, facilitating adherence monitoring, coordinating central resources, and providing reports to the independent Data and Safety Monitoring Board (DSMB). The Imaging Coordinating Center at Cleveland Clinic (led by CSW and XL) manages and coordinates the imaging at each site to ensure uniformity of MRI protocols and image quality and perform centralized image reading and processing. The Biomechanics Coordinating Center at the University of North Carolina at Chapel Hill (led by BP and CL) provides guidance on postoperative physical therapy recommendations and oversees collection, data transmission, and analysis of the biomechanical study outcomes. The Biospecimen Coordinating Center at Duke University School of Medicine (led by VBK and MO) provides oversight for proper collection and analysis of all biological specimens obtained through the study. Finally, the study is supported by an endocrinologist who has performed metformin-related clinical trials in both diabetic and non-diabetic populations, and through active participation from the study sponsor (the Arthritis Foundation). During project preparation, several study groups, including a study-wide operations committee and a clinical committee of the enrolling study surgeons, met regularly to finalize study details.
| Financiadores |
|---|
| Arthritis Foundation |
ASJC Scopus subject areas
- Biomedical Engineering
- Orthopedics and Sports Medicine
- Rehabilitation
Huella
Profundice en los temas de investigación de 'Corrigendum to “The PIKASO trial (Preventing Injured Knees from Osteoarthritis: Severity Outcomes): Rationale and design features for a randomized controlled trial” [Osteoarthr Cartil Open 7 (2025) 100563] (Osteoarthritis and Cartilage Open (2025) 7(1), (S2665913124001304), (10.1016/j.ocarto.2024.100563))'. En conjunto forman una huella única.Citar esto
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