Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Ahmad Al-Attar; Steven R. Presnell; Charlotte A. Peterson; D. Travis Thomas; Charles T. Lutz

doi:10.1016/j.dib.2016.06.006

Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Ahmad Al-Attar
, Steven R. Presnell
, Charlotte A. Peterson
, D. Travis Thomas
, Charles T. Lutz

Producción científica: Article › revisión exhaustiva

5 Citas (Scopus)

Resumen

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56^dim NK cell responses to a variety of stimuli and with CD56^bright/CD56^dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56^dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].

Idioma original	English
Páginas (desde-hasta)	536-544
Número de páginas	9
Publicación	Data in Brief
Volumen	8
DOI	https://doi.org/10.1016/j.dib.2016.06.006
Estado	Published - sept 1 2016

Nota bibliográfica

Publisher Copyright:
© 2016 Published by Elsevier Inc.

Financiación

We thank Jody Clasey, Doug Long, Kim Holt, Andrew J. Morris, Maja Redzic, Yuri M. Klyachkin, and CRO nurses for help with study subjects and data analysis. We thank Suzanne Segerstrom and Philip Westgate for statistical advice. This work was supported by NIH grant, AG040542 , and by University of Kentucky Center for Clinical and Translational Science Analytics Lab and CTSA funding UL1TR000117 .

Financiadores	Número del financiador
National Institutes of Health (NIH)	AG040542
University of Kentucky, Center for Clinical and Translational Science	UL1TR000117

ASJC Scopus subject areas

General

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abstract = "We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].",

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AU - Al-Attar, Ahmad

AU - Presnell, Steven R.

AU - Peterson, Charlotte A.

AU - Thomas, D. Travis

AU - Lutz, Charles T.

PY - 2016/9/1

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AB - We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].

KW - Adiponectin

KW - Ageing

KW - C-reactive protein

KW - Cytomegalovirus

KW - IL-15

KW - NK cell

KW - Retinol binding protein-4

KW - Sex factors

KW - Sphingosine-1-phosphate

KW - T cell

KW - Vitamin D

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JO - Data in Brief

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Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

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