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Deep brain stimulation: Challenges at the tissue-electrode interface and current solutions

Producción científica: Articlerevisión exhaustiva

28 Citas (Scopus)

Resumen

Deep brain stimulation (DBS) is used to treat the motor symptoms of Parkinson's disease patients by stimulating the subthalamic nucleus. However, optimization of DBS is still needed since the performance of the neural electrodes is limited by the body's response to the implant. This review discusses the issues with DBS, such as placement of electrodes, foreign body response, and electrode degradation. The current solutions to these technical issues include modifications to electrode material, coatings, and geometry.

Idioma originalEnglish
Número de artículoe3179
PublicaciónBiotechnology Progress
Volumen37
N.º5
DOI
EstadoPublished - sept 1 2021

Nota bibliográfica

Publisher Copyright:
© 2021 American Institute of Chemical Engineers.

Financiación

The authors would like to thank Dr. Kristen Labazzo and Dr. Li Cai for their comments. This review was submitted by Emily Kolaya as part of the requirements for a Masters in Engineering from the Department of Biomedical Engineering at The State University of New Jersey.

Financiadores
Biomedical Engineering
The State University of New Jersey

    ASJC Scopus subject areas

    • Biotechnology

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