TY - JOUR
T1 - Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure
AU - Chung, Misook L.
AU - Lennie, Terry A.
AU - Dekker, Rebecca L.
AU - Wu, Jia Rong
AU - Moser, Debra K.
PY - 2011/11
Y1 - 2011/11
N2 - Background: Depressive symptoms and poor social support are predictors of increased morbidity and mortality in patients with heart failure (HF). However, the combined contribution of depressive symptoms and social support event-free survival of patients with HF has not been examined. Objective: To compare event-free survival in 4 groups of patients with HF stratified by depressive symptoms and perceived social support (PSS). Method: A total of 220 patients completed the Beck Depression Inventory-II and the Multidimensional Perceived Social Support Scale and were followed for up to 4 years to collect data on death and hospitalizations. Results: Depressive symptoms (hazard ratio = 1.73, P = .008) and PSS (hazard ratio = 1.51, P = .048) were independent predictors of event-free survival. Depressed patients with low PSS had 2.1 times higher risk of events than non-depressed patients with high PSS (P = .003). Conclusion: Depressive symptoms and poor social support had a negative additive effect on event-free survival in patients with HF.
AB - Background: Depressive symptoms and poor social support are predictors of increased morbidity and mortality in patients with heart failure (HF). However, the combined contribution of depressive symptoms and social support event-free survival of patients with HF has not been examined. Objective: To compare event-free survival in 4 groups of patients with HF stratified by depressive symptoms and perceived social support (PSS). Method: A total of 220 patients completed the Beck Depression Inventory-II and the Multidimensional Perceived Social Support Scale and were followed for up to 4 years to collect data on death and hospitalizations. Results: Depressive symptoms (hazard ratio = 1.73, P = .008) and PSS (hazard ratio = 1.51, P = .048) were independent predictors of event-free survival. Depressed patients with low PSS had 2.1 times higher risk of events than non-depressed patients with high PSS (P = .003). Conclusion: Depressive symptoms and poor social support had a negative additive effect on event-free survival in patients with HF.
KW - Chronic Heart Failure
KW - Depression
KW - Outcomes
KW - Social Support
UR - https://www.scopus.com/pages/publications/80054007168
UR - https://www.scopus.com/pages/publications/80054007168#tab=citedBy
U2 - 10.1016/j.hrtlng.2010.08.001
DO - 10.1016/j.hrtlng.2010.08.001
M3 - Article
C2 - 21453972
AN - SCOPUS:80054007168
SN - 0147-9563
VL - 40
SP - 492
EP - 501
JO - Heart and Lung: Journal of Acute and Critical Care
JF - Heart and Lung: Journal of Acute and Critical Care
IS - 6
ER -