Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

Lei Zhang; Xiaojie Chen; Jun Liu; Qingzhang Zhu; Ying Leng; Xiaomin Luo; Hualiang Jiang; Hong Liu

doi:10.1016/j.ejmech.2012.06.020

Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

Lei Zhang
, Xiaojie Chen
, Jun Liu
, Qingzhang Zhu
, Ying Leng
, Xiaomin Luo
, Hualiang Jiang
, Hong Liu

Producción científica: Article › revisión exhaustiva

Idioma original	English
Páginas (desde-hasta)	624-639
Número de páginas	16
Publicación	European Journal of Medicinal Chemistry
Volumen	58
DOI	https://doi.org/10.1016/j.ejmech.2012.06.020
Estado	Published - dic 2012

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

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10.1016/j.ejmech.2012.06.020

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@article{ee0c88911f0b4e03a887c082419b2975,

title = "Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase",

keywords = "Dual-target-directed, Glucokinase activators, Glycogen phosphorylase inhibitors, Hybrid, Type 2 diabetes",

author = "Lei Zhang and Xiaojie Chen and Jun Liu and Qingzhang Zhu and Ying Leng and Xiaomin Luo and Hualiang Jiang and Hong Liu",

year = "2012",

month = dec,

doi = "10.1016/j.ejmech.2012.06.020",

language = "English",

volume = "58",

pages = "624--639",

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TY - JOUR

T1 - Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

AU - Zhang, Lei

AU - Chen, Xiaojie

AU - Liu, Jun

AU - Zhu, Qingzhang

AU - Leng, Ying

AU - Luo, Xiaomin

AU - Jiang, Hualiang

AU - Liu, Hong

PY - 2012/12

Y1 - 2012/12

KW - Dual-target-directed

KW - Glucokinase activators

KW - Glycogen phosphorylase inhibitors

KW - Hybrid

KW - Type 2 diabetes

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U2 - 10.1016/j.ejmech.2012.06.020

DO - 10.1016/j.ejmech.2012.06.020

M3 - Article

C2 - 23178962

SN - 0223-5234

VL - 58

SP - 624

EP - 639

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -

Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

ODS de las Naciones Unidas

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Huella

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