@article{9fa18b41428c40628fb372fa8fef25c2,
title = "Dose-response relationship between light irradiance and the suppression of plasma melatonin in human volunteers",
abstract = "This study tested the capacity of different irradiances of monochromatic light to reduce plasma melatonin in normal humans. Six healthy male volunteers, 24-34 years old, were exposed to 0.01, 0.3, 1.6,5, or 13 μW/cm2 of 509 nm monochromatic light for 1 h during the night on separate occasions. Light irradiance depressed plasma melatonin in a dose-response pattern. The data indicate that the mean threshold irradiance for suppressing melatonin is between 1.6 and 5μW/cm2. Individual variations in threshold responses to monochromatic light were observed among the volunteers.",
keywords = "Circadian, Light, Melatonin, Pineal, Wavelength",
author = "Brainard, \{George C.\} and Lewy, \{Alfred J.\} and Michael Menaker and Fredrickson, \{Richard H.\} and Miller, \{L. Stephen\} and Weleber, \{Richard G.\} and Vincent Cassone and David Hudson",
year = "1988",
month = jun,
day = "28",
doi = "10.1016/0006-8993(88)90820-7",
language = "English",
volume = "454",
pages = "212--218",
number = "1-2",
}