TY - JOUR
T1 - Effects of age-dependent or liposome-induced alterations in the phospholipid composition on sphingomyelin biosynthesis in rat liver microsomal and plasma membranes
AU - Petkova, Diana H.
AU - Nikolova, Mariana N.
AU - Kochlukova, Svetlana E.
AU - Koumanov, Kamen S.
PY - 1991
Y1 - 1991
N2 - 1. 1. The effects of age-dependent or liposome-induced alterations in the phospholipid composition of rat liver plasma and microsomal membranes on the phosphatidylethanolamine:ceramide-phosphoethanolamine (PE:Cer-PEt) and phosphatidylcholine:ceramide-phosphocholine (PC:Cer-PCh) transferase activities were studied. 2. 2. In all cases under study the PE:Cer-PEt transferase activity was found to be several times higher than that of PC: Cer-PCh transferase in both plasma and microsomal rat liver membranes. 3. 3. The presence of phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) in plasma membranes was observed to enhance the PE:Cer-PEt transferase activity, while phosphatidylserine (PS) inhibited it.
AB - 1. 1. The effects of age-dependent or liposome-induced alterations in the phospholipid composition of rat liver plasma and microsomal membranes on the phosphatidylethanolamine:ceramide-phosphoethanolamine (PE:Cer-PEt) and phosphatidylcholine:ceramide-phosphocholine (PC:Cer-PCh) transferase activities were studied. 2. 2. In all cases under study the PE:Cer-PEt transferase activity was found to be several times higher than that of PC: Cer-PCh transferase in both plasma and microsomal rat liver membranes. 3. 3. The presence of phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) in plasma membranes was observed to enhance the PE:Cer-PEt transferase activity, while phosphatidylserine (PS) inhibited it.
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U2 - 10.1016/0020-711X(91)90039-P
DO - 10.1016/0020-711X(91)90039-P
M3 - Article
C2 - 1650720
AN - SCOPUS:0026087110
SN - 0020-711X
VL - 23
SP - 689
EP - 693
JO - International Journal of Biochemistry
JF - International Journal of Biochemistry
IS - 7-8
ER -