TY - GEN
T1 - Effects of spatio-temporal conduction anisotropy on critical interval and coherence
AU - Moghe, S.
AU - Patwardhan, A.
AU - Leonelli, F.
PY - 1999
Y1 - 1999
N2 - We hypothesized that spatio-temporal anisotropy may lead to changes in critical interval and time-coherence that are observed experimentally. To test our hypothesis we performed numerical simulations. Using an S1-S2 protocol, rotors were induced in the left and right half of a 128×128 matrix of cells using a Fitzhugh-Nagumo model. Midway through the simulations pseudo potassium conductance (gk) was changed in one half of the matrix. This caused the two rotors to become asynchronous in rotational velocity. We observed that the average coherence was high when the rotors were synchronous and it was low when the rotors became asynchronous. For different combinations of gk and pseudo-sodium conductance (gNa) we observed a pronounced change in the critical interval.
AB - We hypothesized that spatio-temporal anisotropy may lead to changes in critical interval and time-coherence that are observed experimentally. To test our hypothesis we performed numerical simulations. Using an S1-S2 protocol, rotors were induced in the left and right half of a 128×128 matrix of cells using a Fitzhugh-Nagumo model. Midway through the simulations pseudo potassium conductance (gk) was changed in one half of the matrix. This caused the two rotors to become asynchronous in rotational velocity. We observed that the average coherence was high when the rotors were synchronous and it was low when the rotors became asynchronous. For different combinations of gk and pseudo-sodium conductance (gNa) we observed a pronounced change in the critical interval.
UR - https://www.scopus.com/pages/publications/0033354923
UR - https://www.scopus.com/pages/publications/0033354923#tab=citedBy
M3 - Conference contribution
AN - SCOPUS:0033354923
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 321
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -