Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria

Karen F. Novak; William J. Diamond; Sreenatha Kirakodu; Rebecca Peyyala; Kimberly W. Anderson; Ronald C. Montelaro; Timothy A. Mietzner

doi:10.1128/AAC.00924-06

Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria

Karen F. Novak
, William J. Diamond
, Sreenatha Kirakodu
, Rebecca Peyyala
, Kimberly W. Anderson
, Ronald C. Montelaro
, Timothy A. Mietzner

Producción científica: Article › revisión exhaustiva

13 Citas (Scopus)

Resumen

The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.

Idioma original	English
Páginas (desde-hasta)	1837-1839
Número de páginas	3
Publicación	Antimicrobial Agents and Chemotherapy
Volumen	51
N.º	5
DOI	https://doi.org/10.1128/AAC.00924-06
Estado	Published - may 2007

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.00924-06

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abstract = "The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.",

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AU - Novak, Karen F.

AU - Diamond, William J.

AU - Kirakodu, Sreenatha

AU - Peyyala, Rebecca

AU - Anderson, Kimberly W.

AU - Montelaro, Ronald C.

AU - Mietzner, Timothy A.

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Y1 - 2007/5

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AB - The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.

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ER -

Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria

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