Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging

David P. Cummins; Jordan R. Connor; Katherine A. Heller; Joshua S. Hubert; Megan J. Kates; Katarina R. Wisniewski; Jeffrey C. Berliner; Denise R. O’Dell; James M. Elliott; Kenneth A. Weber; Andrew C. Smith

doi:10.1038/s41394-019-0164-1

Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging

David P. Cummins
, Jordan R. Connor
, Katherine A. Heller
, Joshua S. Hubert
, Megan J. Kates
, Katarina R. Wisniewski
, Jeffrey C. Berliner
, Denise R. O’Dell
, James M. Elliott
, Kenneth A. Weber
, Andrew C. Smith

Physical Therapy

Producción científica: Article › revisión exhaustiva

17 Citas (Scopus)

Resumen

Study design: Retrospective study. Objectives: To establish the inter-rater reliability in the quantitative evaluation of spinal cord damage following cervical incomplete spinal cord injury (SCI) utilizing magnetic resonance imaging (MRI). MRI was used to perform manual measurements of the cranial and caudal boundaries of edema, edema length, midsagittal tissue bridge ratio, axial damage ratio, and edema volume in 10 participants with cervical incomplete SCI. Setting: Academic university setting. Methods: Structural MRIs of 10 participants with SCI were collected from Northwestern University’s Neuromuscular Imaging and Research Lab. All manual measures were performed using OsiriX (Pixmeo Sarl, Geneva, Switzerland). Intraclass correlation coefficients (ICC) were used to determine inter-rater reliability across seven raters of varying experience. Results: High-to-excellent inter-rater reliability was found for all measures. ICC values for cranial/caudal levels of involvement, edema length, midsagittal tissue bridge ratio, axial damage ratio, and edema volume were 0.99, 0.98, 0.90, 0.84, and 0.93, respectively. Conclusions: Manual MRI measures of spinal cord damage are reliable between raters. Researchers and clinicians may confidently utilize manual MRI measures to quantify cord damage. Future research to predict functional recovery following SCI and better inform clinical management is warranted.

Idioma original	English
Número de artículo	20
Publicación	Spinal cord series and cases
Volumen	5
N.º	1
DOI	https://doi.org/10.1038/s41394-019-0164-1
Estado	Published - dic 1 2019

Nota bibliográfica

Publisher Copyright:
© 2019, International Spinal Cord Society.

Financiación

Acknowledgements The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. ACS, KAW, JME, DRO, and JCB were supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development under award number R03HD094577. KAW was supported by the National Institute on Drug Abuse under award number T32DA035165 and the National Institute of Neurological Disorders and Stroke under award number K23NS104211. JME and ACS were supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development under award number R01HD079076. ACS was supported by the Regis University Research and Scholarship Council.

Financiadores	Número del financiador
National Institute of Child Health and Human Development
Regis University Research and Scholarship Council
Eunice Kennedy Shriver National Institute of Child Health and Human Development Cooperative Multicenter Neonatal Research Network	R03HD094577, R01HD079076
Author National Institute on Drug Abuse DA031791 Mark J Ferris National Institute on Drug Abuse DA006634 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA026117 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA028162 Elizabeth G Pitts National Institute of General Medical Sciences GM102773 Elizabeth G Pitts Peter McManus Charitable Trust Mark J Ferris National Institute on Drug Abuse	T32DA035165
Institute of Neurological Disorders and Stroke National Advisory Neurological Disorders and Stroke Council	K23NS104211

ASJC Scopus subject areas

Neurology
Clinical Neurology

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Cummins, D. P., Connor, J. R., Heller, K. A., Hubert, J. S., Kates, M. J., Wisniewski, K. R., Berliner, J. C., O’Dell, D. R., Elliott, J. M., Weber, K. A., & Smith, A. C. (2019). Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging. Spinal cord series and cases, 5(1), Artículo 20. https://doi.org/10.1038/s41394-019-0164-1

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abstract = "Study design: Retrospective study. Objectives: To establish the inter-rater reliability in the quantitative evaluation of spinal cord damage following cervical incomplete spinal cord injury (SCI) utilizing magnetic resonance imaging (MRI). MRI was used to perform manual measurements of the cranial and caudal boundaries of edema, edema length, midsagittal tissue bridge ratio, axial damage ratio, and edema volume in 10 participants with cervical incomplete SCI. Setting: Academic university setting. Methods: Structural MRIs of 10 participants with SCI were collected from Northwestern University{\textquoteright}s Neuromuscular Imaging and Research Lab. All manual measures were performed using OsiriX (Pixmeo Sarl, Geneva, Switzerland). Intraclass correlation coefficients (ICC) were used to determine inter-rater reliability across seven raters of varying experience. Results: High-to-excellent inter-rater reliability was found for all measures. ICC values for cranial/caudal levels of involvement, edema length, midsagittal tissue bridge ratio, axial damage ratio, and edema volume were 0.99, 0.98, 0.90, 0.84, and 0.93, respectively. Conclusions: Manual MRI measures of spinal cord damage are reliable between raters. Researchers and clinicians may confidently utilize manual MRI measures to quantify cord damage. Future research to predict functional recovery following SCI and better inform clinical management is warranted.",

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AU - Kates, Megan J.

AU - Wisniewski, Katarina R.

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Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging

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