Evaluation of occlusal splint therapy: A research design

Occlusal splints have been widely used in dentistry for treating craniomandibular disorders, yet the precise effect that splints have on symptoms is still undetermined. When the available research evidence is closely scrutinized it is found to be weak and generally unsupported. Most studies are lacking in sound research design and often draw conclusions that are unsubstantiated. Recognizing these weaknesses, this article proposes a research design that will effectively evaluate treatment effects through rigid, well-controlled, and accurately documented experimentation. Using this research design clinically may be a difficult task. However, incorporation of one or more of the suggested parameters will help to strengthen any research proposal.