Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase

Dwight C. German; Gordon Bruce; Louis B. Hersh

doi:10.1016/0304-3940(85)90391-X

Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase

Dwight C. German
, Gordon Bruce
, Louis B. Hersh

Producción científica: Article › revisión exhaustiva

96 Citas (Scopus)

Resumen

Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.

Idioma original	English
Páginas (desde-hasta)	1-5
Número de páginas	5
Publicación	Neuroscience Letters
Volumen	61
N.º	1-2
DOI	https://doi.org/10.1016/0304-3940(85)90391-X
Estado	Published - oct 24 1985

Financiación

Financiadores	Número del financiador
National Institute of Neurological Disorders and Stroke	R01NS015739

ODS de las Naciones Unidas

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ASJC Scopus subject areas

General Neuroscience

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title = "Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase",

abstract = "Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.",

keywords = "choline acetyltransferase, human brain, immunohistochemistry",

author = "German, \{Dwight C.\} and Gordon Bruce and Hersh, \{Louis B.\}",

year = "1985",

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doi = "10.1016/0304-3940(85)90391-X",

language = "English",

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T1 - Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase

AU - German, Dwight C.

AU - Bruce, Gordon

AU - Hersh, Louis B.

PY - 1985/10/24

Y1 - 1985/10/24

N2 - Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.

AB - Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.

KW - choline acetyltransferase

KW - human brain

KW - immunohistochemistry

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UR - https://www.scopus.com/pages/publications/0022347355#tab=citedBy

U2 - 10.1016/0304-3940(85)90391-X

DO - 10.1016/0304-3940(85)90391-X

M3 - Article

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AN - SCOPUS:0022347355

SN - 0304-3940

VL - 61

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JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 1-2

ER -

Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase

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