Lack of effect of entorhinal kindling on l-[3H]glutamic acid presynaptic uptake and postsynaptic binding in hippocampus

John T. Slevin; Lindley P. Ferrara

doi:10.1016/0014-4886(85)90264-X

Lack of effect of entorhinal kindling on l-[³H]glutamic acid presynaptic uptake and postsynaptic binding in hippocampus

John T. Slevin
, Lindley P. Ferrara

Producción científica: Article › revisión exhaustiva

25 Citas (Scopus)

Resumen

Sodium-independent l-[³H]glutamic acid binding and sodium-dependent l-[³H]glutamic acid high affinity uptake were measured in hippocampal membranes of rats administered electroshock seizures or kindled to class 5 seizures by entorhinal cortical stimulation. There were no differences in these glutamatergic synaptic markers among electroshocked, kindled, or surgical control animals. Entorhinal kindling is not a reflection of activity-regulated facilitation of perforant path glutamatergic neurotransmission.

Idioma original	English
Páginas (desde-hasta)	48-58
Número de páginas	11
Publicación	Experimental Neurology
Volumen	89
N.º	1
DOI	https://doi.org/10.1016/0014-4886(85)90264-X
Estado	Published - jul 1985

Nota bibliográfica

Funding Information:
Abbreviations: LTP-long-term potentiation. ’ This work was supported in part by the Veterans Administration and the National Institutes of Health (TIDA NSO0732 to J.T.S.). We thank Patricia Lee for preparation of the manuscript. Please send reprint requests to J.T.S.

Financiación

Abbreviations: LTP-long-term potentiation. ’ This work was supported in part by the Veterans Administration and the National Institutes of Health (TIDA NSO0732 to J.T.S.). We thank Patricia Lee for preparation of the manuscript. Please send reprint requests to J.T.S.

Financiadores	Número del financiador
Veterans Administration
National Institutes of Health (NIH)	TIDA NSO0732
National Institute of Neurological Disorders and Stroke	K07NS000732

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

Acceder al documento

10.1016/0014-4886(85)90264-X

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