Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull; Mark E. Thompson; Linda Smith; C. Darrell Jennings; Michael A. Doukas; Edward J. Pavlik; Deborah E. Powell

doi:10.1002/ajh.2830240309

Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull
, Mark E. Thompson
, Linda Smith
, C. Darrell Jennings
, Michael A. Doukas
, Edward J. Pavlik
, Deborah E. Powell

Producción científica: Article › revisión exhaustiva

5 Citas (Scopus)

Resumen

The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

Idioma original	English
Páginas (desde-hasta)	293-299
Número de páginas	7
Publicación	American Journal of Hematology
Volumen	24
N.º	3
DOI	https://doi.org/10.1002/ajh.2830240309
Estado	Published - mar 1987

ASJC Scopus subject areas

Hematology

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title = "Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature",

abstract = "The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.",

keywords = "blast phase chronic myelogenous leukemia, cytogenetics, hypodiploidy",

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AU - Jennings, C. Darrell

AU - Doukas, Michael A.

AU - Pavlik, Edward J.

AU - Powell, Deborah E.

PY - 1987/3

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AB - The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

KW - blast phase chronic myelogenous leukemia

KW - cytogenetics

KW - hypodiploidy

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UR - https://www.scopus.com/pages/publications/0023138393#tab=citedBy

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Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

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