Neuropsychological functioning in hemiparkinsonism

Lee Xenakis Blonder; Raquel E. Gur; Ruben C. Gur; Andrew J. Saykin; Howard I. Hurtig

doi:10.1016/0278-2626(89)90034-1

Neuropsychological functioning in hemiparkinsonism

Lee Xenakis Blonder
, Raquel E. Gur
, Ruben C. Gur
, Andrew J. Saykin
, Howard I. Hurtig

Producción científica: Article › revisión exhaustiva

64 Citas (Scopus)

Resumen

A standardized neuropsychological battery including measures of intellectual cognitive, memory, attention-concentration, language, abstraction and mental flexibility, and sensory and motor functions was administered to 21 hemiparkinsonian patients (14 with right side and 7 with left side symptoms) and 17 controls matched for age and education. Patients were impaired in all functions except sensory. For motor functions, impairment was ipsilateral to the side of symptoms. For cognitive functions, right side symptoms were associated with verbal deficits whereas left side symptoms were associated with spatial deficits. Thus, a pattern of neuropsychological deficits consistent with the lateralization of motor symptoms may appear in the early stages of the disease.

Idioma original	English
Páginas (desde-hasta)	244-257
Número de páginas	14
Publicación	Brain and Cognition
Volumen	9
N.º	2
DOI	https://doi.org/10.1016/0278-2626(89)90034-1
Estado	Published - mar 1989

Nota bibliográfica

Funding Information:
This study was performed as a part of a dissertation by the first author in partial fulfillment of the requirements for a Ph.D. in Anthropology at the University of Pennsylvania. The work was supported by Grants MH 30456, MH 00586, AG 41915, and AG 05583. We thank Gwyn Vernon, Beth Rosenwasser, and the Graduate Hospital Movement Disorder Center staff; John Fought, Francis Johnston, and Solomon Katz of the Department of Anthropology at Penn, and Edward Foulkes, Department of Psychiatry at Tulane, for their guidance; Susan Resnick and Brett Skolnick of the Brain Behavior Laboratory at Penn for assistance with data analysis; Steven Kanes and Robert Kass, who were Research Assistants; and the individuals who participated in the study. Address correspondence and reprint requests to Dr. R. E. Gur, Brain Behavior Laboratory, Department of Psychiatry, 205 Piersol Building, University of Pennsylvania, Philadelphia, PA 19104.

Financiación

This study was performed as a part of a dissertation by the first author in partial fulfillment of the requirements for a Ph.D. in Anthropology at the University of Pennsylvania. The work was supported by Grants MH 30456, MH 00586, AG 41915, and AG 05583. We thank Gwyn Vernon, Beth Rosenwasser, and the Graduate Hospital Movement Disorder Center staff; John Fought, Francis Johnston, and Solomon Katz of the Department of Anthropology at Penn, and Edward Foulkes, Department of Psychiatry at Tulane, for their guidance; Susan Resnick and Brett Skolnick of the Brain Behavior Laboratory at Penn for assistance with data analysis; Steven Kanes and Robert Kass, who were Research Assistants; and the individuals who participated in the study. Address correspondence and reprint requests to Dr. R. E. Gur, Brain Behavior Laboratory, Department of Psychiatry, 205 Piersol Building, University of Pennsylvania, Philadelphia, PA 19104.

Financiadores	Número del financiador
National Institute of Mental Health	R01MH030456

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Experimental and Cognitive Psychology
Developmental and Educational Psychology
Arts and Humanities (miscellaneous)
Cognitive Neuroscience

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title = "Neuropsychological functioning in hemiparkinsonism",

abstract = "A standardized neuropsychological battery including measures of intellectual cognitive, memory, attention-concentration, language, abstraction and mental flexibility, and sensory and motor functions was administered to 21 hemiparkinsonian patients (14 with right side and 7 with left side symptoms) and 17 controls matched for age and education. Patients were impaired in all functions except sensory. For motor functions, impairment was ipsilateral to the side of symptoms. For cognitive functions, right side symptoms were associated with verbal deficits whereas left side symptoms were associated with spatial deficits. Thus, a pattern of neuropsychological deficits consistent with the lateralization of motor symptoms may appear in the early stages of the disease.",

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Neuropsychological functioning in hemiparkinsonism

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Financiación

ASJC Scopus subject areas

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