Pancreatic Insufficiency: What Is the Gold Standard?

Maisam Abu-El-Haija; Darwin L. Conwell

doi:10.1016/j.giec.2018.05.004

Pancreatic Insufficiency: What Is the Gold Standard?

Maisam Abu-El-Haija
, Darwin L. Conwell

Producción científica: Review article › revisión exhaustiva

9 Citas (Scopus)

Resumen

Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

Idioma original	English
Páginas (desde-hasta)	521-528
Número de páginas	8
Publicación	Gastrointestinal Endoscopy Clinics of North America
Volumen	28
N.º	4
DOI	https://doi.org/10.1016/j.giec.2018.05.004
Estado	Published - oct 2018

Nota bibliográfica

Publisher Copyright:
© 2018 Elsevier Inc.

Financiación

Disclosures: In-kind support for investigator-initiated grant from ChiRhoClin, Inc was received for the MR study (M. Abu-El-Haija). The National Pancreas Foundation funded parts of the Pancreatic Function Studies using MRI (M. Abu-El-Haija). This study was supported by the National Cancer Institute and National Institute of Diabetes and Digestive and Kidney Diseases under award number U01DK108327 (D.L. Conwell). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Financiadores	Número del financiador
Pancreatic Function Studies using MRI
National Institutes of Health (NIH)
National Childhood Cancer Registry – National Cancer Institute
National Institute of Diabetes and Digestive and Kidney Diseases	U01DK108327
National Pancreas Foundation

ASJC Scopus subject areas

Gastroenterology

Acceder al documento

10.1016/j.giec.2018.05.004

Otros archivos y enlaces

Citar esto

@article{bd0b0cfcb052402b800df2f91c4f91c7,

title = "Pancreatic Insufficiency: What Is the Gold Standard?",

abstract = "Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.",

keywords = "Chronic pancreatitis, Endoscopic function testing, Pancreatic function testing, Pancreatic insufficiency",

author = "Maisam Abu-El-Haija and Conwell, \{Darwin L.\}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = oct,

doi = "10.1016/j.giec.2018.05.004",

language = "English",

volume = "28",

pages = "521--528",

journal = "Gastrointestinal Endoscopy Clinics of North America",

issn = "1052-5157",

publisher = "W.B. Saunders",

number = "4",

}

TY - JOUR

T1 - Pancreatic Insufficiency

T2 - What Is the Gold Standard?

AU - Abu-El-Haija, Maisam

AU - Conwell, Darwin L.

PY - 2018/10

Y1 - 2018/10

N2 - Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

AB - Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

KW - Chronic pancreatitis

KW - Endoscopic function testing

KW - Pancreatic function testing

KW - Pancreatic insufficiency

UR - https://www.scopus.com/pages/publications/85048931924

UR - https://www.scopus.com/pages/publications/85048931924#tab=citedBy

U2 - 10.1016/j.giec.2018.05.004

DO - 10.1016/j.giec.2018.05.004

M3 - Review article

C2 - 30241641

AN - SCOPUS:85048931924

SN - 1052-5157

VL - 28

SP - 521

EP - 528

JO - Gastrointestinal Endoscopy Clinics of North America

JF - Gastrointestinal Endoscopy Clinics of North America

IS - 4

ER -

Pancreatic Insufficiency: What Is the Gold Standard?

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto