TY - JOUR
T1 - Pharmacokinetic alterations of antimicrobials in the critically ill
AU - Cook, Aaron M.
PY - 2005/4
Y1 - 2005/4
N2 - Critical illness is accompanied by multiple physiologic alterations that affect the pharmacokinetics of antimicrobials. Although the pharmacokinetics of a number of antimicrobials have been studied in critically ill individuals, an understanding of the physiological alterations in critical illness and general pharmacokinetic principles of antimicrobials is imperative for appropriate selection, dosing, and prediction of toxicity.
AB - Critical illness is accompanied by multiple physiologic alterations that affect the pharmacokinetics of antimicrobials. Although the pharmacokinetics of a number of antimicrobials have been studied in critically ill individuals, an understanding of the physiological alterations in critical illness and general pharmacokinetic principles of antimicrobials is imperative for appropriate selection, dosing, and prediction of toxicity.
KW - Adult
KW - Antimicrobials
KW - Critical illness
KW - Pharmacokinetics
UR - https://www.scopus.com/pages/publications/16344380591
UR - https://www.scopus.com/inward/citedby.url?scp=16344380591&partnerID=8YFLogxK
U2 - 10.1177/0897190004273568
DO - 10.1177/0897190004273568
M3 - Review article
AN - SCOPUS:16344380591
SN - 0897-1900
VL - 18
SP - 75
EP - 83
JO - Journal of Pharmacy Practice
JF - Journal of Pharmacy Practice
IS - 2
ER -