@inproceedings{f9fa721dfac746aa9e5b7beffa430810,
title = "Polyketide biosynthesis beyond the type I, II, and III polyketide synthase paradigms: A progress report",
abstract = "The archetypical polyketide synthases (PKSs), known as type I, II, and III PKSs, have accounted for the vast structural diversities embodied by polyketide natural products, but recent progress in polyketide biosynthesis clearly suggests much greater diversity for PKS mechanism and structure. We have previously argued the emergence of novel PKSs and cautioned the oversimplification of polyketide biosynthesis according to the type I, II, and III PKS paradigms on the basis of our studies on the biosynthesis of the enediynes, the macrotetrolides, and leinamycin. We present here a brief progress report on our current effort to mechanistically characterize these novel PKSs.",
author = "Ben Shen and Cheng, \{Yi Qiang\} and Christenson, \{Steven D.\} and Hui Jiang and Jianhua Ju and Kwon, \{Hyung Jin\} and Lim, \{Si Kyu\} and Wen Liu and Koichi Nonaka and Seo, \{Jeong Woo\} and Smith, \{Wyatt C.\} and Scott Standage and Tang, \{Gong Li\} and \{Van Lanen\}, Steven and Jian Zhang",
year = "2007",
language = "English",
isbn = "0841239789",
series = "ACS Symposium Series",
pages = "154--166",
editor = "Agnes Rimando and Scott Baerson",
booktitle = "Polyketides Biosynthesis, Biological Activity, and Genetic Engineering",
}