Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile

Ximena Oyarzún-González; Erin L. Abner; Pablo Toro; Catterina Ferreccio

doi:10.3233/JAD-230541

Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile

Ximena Oyarzún-González, Erin L. Abner, Pablo Toro, Catterina Ferreccio

Producción científica: Article › revisión exhaustiva

1 Cita (Scopus)

Resumen

Background: Subjective memory complaints (SMC) are commonly studied in older adults and have been identified as potentially prodromal to dementia and Alzheimer's disease. Studies among younger adults from South America are lacking. Objective: To estimate the prevalence of SMC and the factors associated with it among Maule Cohort (MAUCO) participants. Methods: We performed a cross-sectional analysis to estimate the prevalence of SMC and investigated its associated factors from MAUCO baseline data (N=6,687). Within groups defined by age (38-59, 60-74) and global cognition (Mini-Mental State Examination: ≥26, 25-22, ≤21), multinomial logistic regression models evaluated risk factors for SMC (Yes, Sometimes, No). Results: Overall, SMC prevalence was 16.4%; 15.9% (95% CI 14.9-16.9%) among younger and 17.6% (15.8-19.4%) among older participants. Female sex, comorbidities, and bad/fair self-reported health status (SRHS) were generally associated with higher odds of SMC. Conclusion: Overall prevalence of SMC was 16%. Different factors were associated with the odds of SMC depending on age and global cognitive status. Future SMC studies should include sex-specific assessments, evaluate SRHS as a moderator of SMC reporting, and the influence of the SARS-CoV-2 pandemic on SMC reporting.

Idioma original	English
Páginas (desde-hasta)	1221-1231
Número de páginas	11
Publicación	Journal of Alzheimer's Disease
Volumen	95
N.º	3
DOI	https://doi.org/10.3233/JAD-230541
Estado	Published - sept 26 2023

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Publisher Copyright:
© 2023 - IOS Press. All rights reserved.

Financiación

The development and management of MAUCO are supported by funding provided by the Chilean government through the National Commission for Scientific & Technological Research (CONICYT) for Research Centers in Priority Areas (FONDAP) [grant number 15130011], and from FONDECYT Project [grant number 1170395]. Furthermore, additional funds come from the Faculty of Medicine and the Vicerectoría de Investigación of Pontificia Universidad Católica de Chile. Dr. Abner is supported by National Institute on Aging P30AG072946. However, the sponsors had no role in the writing process of the present manuscript. The development and management of MAUCO are supported by funding provided by the Chilean government through the National Commission for Scientific & Technological Research (CONICYT) for Research Centers in Priority Areas (FONDAP) [grant number 15130011], and from FONDECYT Project [grant number 1170395]. Furthermore, additional funds come from the Faculty of Medicine and the Vicerectoría de Investigación of Pontificia Universidad Católica de Chile. Dr. Abner is supported by National Institute on Aging P30AG072946. However, the sponsors had no role in the writing process of the present manuscript.

Financiadores	Número del financiador
Vicerectoría de Investigación of Pontificia Universidad Católica de Chile
National Institute on Aging	P30AG072946
National Institute on Aging
Comisión Nacional de Investigación Científica y Tecnológica	15130011
Comisión Nacional de Investigación Científica y Tecnológica
Fondo Nacional de Desarrollo Científico y Tecnológico	1170395
Fondo Nacional de Desarrollo Científico y Tecnológico

ASJC Scopus subject areas

General Neuroscience
Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

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@article{b4df086dca8c4a0f9880fdeb1741a150,

title = "Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile",

abstract = "Background: Subjective memory complaints (SMC) are commonly studied in older adults and have been identified as potentially prodromal to dementia and Alzheimer's disease. Studies among younger adults from South America are lacking. Objective: To estimate the prevalence of SMC and the factors associated with it among Maule Cohort (MAUCO) participants. Methods: We performed a cross-sectional analysis to estimate the prevalence of SMC and investigated its associated factors from MAUCO baseline data (N=6,687). Within groups defined by age (38-59, 60-74) and global cognition (Mini-Mental State Examination: ≥26, 25-22, ≤21), multinomial logistic regression models evaluated risk factors for SMC (Yes, Sometimes, No). Results: Overall, SMC prevalence was 16.4\%; 15.9\% (95\% CI 14.9-16.9\%) among younger and 17.6\% (15.8-19.4\%) among older participants. Female sex, comorbidities, and bad/fair self-reported health status (SRHS) were generally associated with higher odds of SMC. Conclusion: Overall prevalence of SMC was 16\%. Different factors were associated with the odds of SMC depending on age and global cognitive status. Future SMC studies should include sex-specific assessments, evaluate SRHS as a moderator of SMC reporting, and the influence of the SARS-CoV-2 pandemic on SMC reporting.",

keywords = "Alzheimer's disease, MAUCO, cohort, memory, multinomial, subjective memory complaint",

author = "Ximena Oyarz{\'u}n-Gonz{\'a}lez and Abner, \{Erin L.\} and Pablo Toro and Catterina Ferreccio",

year = "2023",

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doi = "10.3233/JAD-230541",

language = "English",

volume = "95",

pages = "1221--1231",

number = "3",

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T1 - Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile

AU - Oyarzún-González, Ximena

AU - Abner, Erin L.

AU - Toro, Pablo

AU - Ferreccio, Catterina

PY - 2023/9/26

Y1 - 2023/9/26

N2 - Background: Subjective memory complaints (SMC) are commonly studied in older adults and have been identified as potentially prodromal to dementia and Alzheimer's disease. Studies among younger adults from South America are lacking. Objective: To estimate the prevalence of SMC and the factors associated with it among Maule Cohort (MAUCO) participants. Methods: We performed a cross-sectional analysis to estimate the prevalence of SMC and investigated its associated factors from MAUCO baseline data (N=6,687). Within groups defined by age (38-59, 60-74) and global cognition (Mini-Mental State Examination: ≥26, 25-22, ≤21), multinomial logistic regression models evaluated risk factors for SMC (Yes, Sometimes, No). Results: Overall, SMC prevalence was 16.4%; 15.9% (95% CI 14.9-16.9%) among younger and 17.6% (15.8-19.4%) among older participants. Female sex, comorbidities, and bad/fair self-reported health status (SRHS) were generally associated with higher odds of SMC. Conclusion: Overall prevalence of SMC was 16%. Different factors were associated with the odds of SMC depending on age and global cognitive status. Future SMC studies should include sex-specific assessments, evaluate SRHS as a moderator of SMC reporting, and the influence of the SARS-CoV-2 pandemic on SMC reporting.

AB - Background: Subjective memory complaints (SMC) are commonly studied in older adults and have been identified as potentially prodromal to dementia and Alzheimer's disease. Studies among younger adults from South America are lacking. Objective: To estimate the prevalence of SMC and the factors associated with it among Maule Cohort (MAUCO) participants. Methods: We performed a cross-sectional analysis to estimate the prevalence of SMC and investigated its associated factors from MAUCO baseline data (N=6,687). Within groups defined by age (38-59, 60-74) and global cognition (Mini-Mental State Examination: ≥26, 25-22, ≤21), multinomial logistic regression models evaluated risk factors for SMC (Yes, Sometimes, No). Results: Overall, SMC prevalence was 16.4%; 15.9% (95% CI 14.9-16.9%) among younger and 17.6% (15.8-19.4%) among older participants. Female sex, comorbidities, and bad/fair self-reported health status (SRHS) were generally associated with higher odds of SMC. Conclusion: Overall prevalence of SMC was 16%. Different factors were associated with the odds of SMC depending on age and global cognitive status. Future SMC studies should include sex-specific assessments, evaluate SRHS as a moderator of SMC reporting, and the influence of the SARS-CoV-2 pandemic on SMC reporting.

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KW - subjective memory complaint

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Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile

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