Progesterone receptor membrane component 1/ Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

Shakeel U.R. Mir; Steven R. Schwarze; Ling Jin; Jinling Zhang; Woodrow Friend; Sumitra Miriyala; Daret St Clair; Rolf J. Craven

doi:10.4161/auto.25889

Progesterone receptor membrane component 1/ Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

Shakeel U.R. Mir
, Steven R. Schwarze
, Ling Jin
, Jinling Zhang
, Woodrow Friend
, Sumitra Miriyala
, Daret St Clair
, Rolf J. Craven

Producción científica: Article › revisión exhaustiva

73 Citas (Scopus)

Resumen

AMPK, AMP-dependent protein kinase; BCL2, B-cell lymphoma 2; BECN1, Beclin 1, autophagy related; CCNA1, cyclin A1; CTSD, cathepsin D; EGFR, epidermal growth factor receptor; FACS, fluorescence-activated cell sorting; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GFP, green fluorescent protein; JNK, c-JUN N-terminal kinase; LAMP1, lysosomal-associated membrane protein 1; MAP1LC3, microtubule-associated protein 1 light chain 3; MMP9, matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase); MTOR, mechanistic target of rapamycin; PGRMC1, progesterone-associated membrane component 1; RPS6KB/p70S6K, ribosomal protein S6 kinase, 70 kDa, polypeptide/ p70 S6 kinase; RNAi, RNA interference; SQSTM1, sequestosome 1; TSC, tuberous sclerosis complex; TUBA, tubulin A; UVRAG, UV radiation-resistance associated; VPS16, vacuolar protein sorting 16 homolog (S. cerevisiae).

Idioma original	English
Páginas (desde-hasta)	1566-1578
Número de páginas	13
Publicación	Autophagy
Volumen	9
N.º	10
DOI	https://doi.org/10.4161/auto.25889
Estado	Published - oct 2013

Nota bibliográfica

Funding Information:
The authors thank Mary Gail Engle and Jim Begley for their expertise with confocal and electron microscopy and Matthew Thacker for expert technical assistance. This work supported by grants from the Kentucky Lung Cancer Research Program, the Bonnie Addario Lung Cancer Foundation and the Kentucky Science and Education Fund (KSEF-2064-RDE-013).

Financiación

The authors thank Mary Gail Engle and Jim Begley for their expertise with confocal and electron microscopy and Matthew Thacker for expert technical assistance. This work supported by grants from the Kentucky Lung Cancer Research Program, the Bonnie Addario Lung Cancer Foundation and the Kentucky Science and Education Fund (KSEF-2064-RDE-013).

Financiadores	Número del financiador
Kentucky Lung Cancer Research Program
Kentucky Science and Education Fund	KSEF-2064-RDE-013
Bonnie J Addario Lung Cancer Foundation

ASJC Scopus subject areas

Molecular Biology
Cell Biology

Acceder al documento

10.4161/auto.25889

Otros archivos y enlaces

Citar esto

@article{02b2df28647a44a7bf7ee8341aae4fda,

title = "Progesterone receptor membrane component 1/ Sigma-2 receptor associates with MAP1LC3B and promotes autophagy",

abstract = "AMPK, AMP-dependent protein kinase; BCL2, B-cell lymphoma 2; BECN1, Beclin 1, autophagy related; CCNA1, cyclin A1; CTSD, cathepsin D; EGFR, epidermal growth factor receptor; FACS, fluorescence-activated cell sorting; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GFP, green fluorescent protein; JNK, c-JUN N-terminal kinase; LAMP1, lysosomal-associated membrane protein 1; MAP1LC3, microtubule-associated protein 1 light chain 3; MMP9, matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase); MTOR, mechanistic target of rapamycin; PGRMC1, progesterone-associated membrane component 1; RPS6KB/p70S6K, ribosomal protein S6 kinase, 70 kDa, polypeptide/ p70 S6 kinase; RNAi, RNA interference; SQSTM1, sequestosome 1; TSC, tuberous sclerosis complex; TUBA, tubulin A; UVRAG, UV radiation-resistance associated; VPS16, vacuolar protein sorting 16 homolog (S. cerevisiae).",

keywords = "Autophagy, Metabolism, TOR, Therapeutics, Ubiquitin",

author = "Mir, \{Shakeel U.R.\} and Schwarze, \{Steven R.\} and Ling Jin and Jinling Zhang and Woodrow Friend and Sumitra Miriyala and Clair, \{Daret St\} and Craven, \{Rolf J.\}",

note = "Funding Information: The authors thank Mary Gail Engle and Jim Begley for their expertise with confocal and electron microscopy and Matthew Thacker for expert technical assistance. This work supported by grants from the Kentucky Lung Cancer Research Program, the Bonnie Addario Lung Cancer Foundation and the Kentucky Science and Education Fund (KSEF-2064-RDE-013).",

year = "2013",

month = oct,

doi = "10.4161/auto.25889",

language = "English",

volume = "9",

pages = "1566--1578",

number = "10",

}

TY - JOUR

T1 - Progesterone receptor membrane component 1/ Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

AU - Mir, Shakeel U.R.

AU - Schwarze, Steven R.

AU - Jin, Ling

AU - Zhang, Jinling

AU - Friend, Woodrow

AU - Miriyala, Sumitra

AU - Clair, Daret St

AU - Craven, Rolf J.

N1 - Funding Information: The authors thank Mary Gail Engle and Jim Begley for their expertise with confocal and electron microscopy and Matthew Thacker for expert technical assistance. This work supported by grants from the Kentucky Lung Cancer Research Program, the Bonnie Addario Lung Cancer Foundation and the Kentucky Science and Education Fund (KSEF-2064-RDE-013).

PY - 2013/10

Y1 - 2013/10

N2 - AMPK, AMP-dependent protein kinase; BCL2, B-cell lymphoma 2; BECN1, Beclin 1, autophagy related; CCNA1, cyclin A1; CTSD, cathepsin D; EGFR, epidermal growth factor receptor; FACS, fluorescence-activated cell sorting; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GFP, green fluorescent protein; JNK, c-JUN N-terminal kinase; LAMP1, lysosomal-associated membrane protein 1; MAP1LC3, microtubule-associated protein 1 light chain 3; MMP9, matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase); MTOR, mechanistic target of rapamycin; PGRMC1, progesterone-associated membrane component 1; RPS6KB/p70S6K, ribosomal protein S6 kinase, 70 kDa, polypeptide/ p70 S6 kinase; RNAi, RNA interference; SQSTM1, sequestosome 1; TSC, tuberous sclerosis complex; TUBA, tubulin A; UVRAG, UV radiation-resistance associated; VPS16, vacuolar protein sorting 16 homolog (S. cerevisiae).

AB - AMPK, AMP-dependent protein kinase; BCL2, B-cell lymphoma 2; BECN1, Beclin 1, autophagy related; CCNA1, cyclin A1; CTSD, cathepsin D; EGFR, epidermal growth factor receptor; FACS, fluorescence-activated cell sorting; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GFP, green fluorescent protein; JNK, c-JUN N-terminal kinase; LAMP1, lysosomal-associated membrane protein 1; MAP1LC3, microtubule-associated protein 1 light chain 3; MMP9, matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase); MTOR, mechanistic target of rapamycin; PGRMC1, progesterone-associated membrane component 1; RPS6KB/p70S6K, ribosomal protein S6 kinase, 70 kDa, polypeptide/ p70 S6 kinase; RNAi, RNA interference; SQSTM1, sequestosome 1; TSC, tuberous sclerosis complex; TUBA, tubulin A; UVRAG, UV radiation-resistance associated; VPS16, vacuolar protein sorting 16 homolog (S. cerevisiae).

KW - Autophagy

KW - Metabolism

KW - TOR

KW - Therapeutics

KW - Ubiquitin

UR - https://www.scopus.com/pages/publications/84885646346

UR - https://www.scopus.com/pages/publications/84885646346#tab=citedBy

U2 - 10.4161/auto.25889

DO - 10.4161/auto.25889

M3 - Article

C2 - 24113030

AN - SCOPUS:84885646346

SN - 1554-8627

VL - 9

SP - 1566

EP - 1578

JO - Autophagy

JF - Autophagy

IS - 10

ER -

Progesterone receptor membrane component 1/ Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto