Psychopharmacology of the hallucinogenic sage Salvia divinorum

Thomas E. Prisinzano

doi:10.1016/j.lfs.2005.09.008

Psychopharmacology of the hallucinogenic sage Salvia divinorum

Thomas E. Prisinzano

Producción científica: Article › revisión exhaustiva

104 Citas (Scopus)

Resumen

At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

Idioma original	English
Páginas (desde-hasta)	527-531
Número de páginas	5
Publicación	Life Sciences
Volumen	78
N.º	5
DOI	https://doi.org/10.1016/j.lfs.2005.09.008
Estado	Published - dic 22 2005

Nota bibliográfica

Funding Information:
The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

Financiación

The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

Financiadores	Número del financiador
Leander J. Valdés III
National Institute on Drug Abuse	R01DA018151
University of Northern Iowa

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
General Biochemistry, Genetics and Molecular Biology

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10.1016/j.lfs.2005.09.008

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title = "Psychopharmacology of the hallucinogenic sage Salvia divinorum",

abstract = "At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.",

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AU - Prisinzano, Thomas E.

N1 - Funding Information: The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

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N2 - At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

AB - At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

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KW - Kappa

KW - Opioid

KW - Salvia divinorum

KW - Salvinorin A

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Psychopharmacology of the hallucinogenic sage Salvia divinorum

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

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