Red shell- high risk normal tissue in stereotactic radiosurgery

Jun Yang; Weihua Qi; Lei Wang; Qiuxia Lu; Liangfu Han; Brian Wang; Weisi Yan

doi:10.1002/pro6.1218

Red shell- high risk normal tissue in stereotactic radiosurgery

Jun Yang
, Weihua Qi
, Lei Wang
, Qiuxia Lu
, Liangfu Han
, Brian Wang
, Weisi Yan

Producción científica: Review article › revisión exhaustiva

Resumen

Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.

Idioma original	English
Páginas (desde-hasta)	273-277
Número de páginas	5
Publicación	Precision Radiation Oncology
Volumen	7
N.º	4
DOI	https://doi.org/10.1002/pro6.1218
Estado	Published - dic 2023

Nota bibliográfica

Publisher Copyright:
© 2023 The Authors. Precision Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Shandong Cancer Hospital & Institute.

Financiación

The authors are grateful to the pioneers of our field, Jack Fowler Ph.D. and Luther w Brady M.D. for their guidance in preparing and formulating this concept.

ASJC Scopus subject areas

Oncology

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10.1002/pro6.1218

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title = "Red shell- high risk normal tissue in stereotactic radiosurgery",

abstract = "Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.",

keywords = "Red Shell, biological equivalent dose, normal tissue, stereotactic radiosurgery, toxicity",

author = "Jun Yang and Weihua Qi and Lei Wang and Qiuxia Lu and Liangfu Han and Brian Wang and Weisi Yan",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Precision Radiation Oncology published by John Wiley \& Sons Australia, Ltd on behalf of Shandong Cancer Hospital \& Institute.",

year = "2023",

month = dec,

doi = "10.1002/pro6.1218",

language = "English",

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TY - JOUR

T1 - Red shell- high risk normal tissue in stereotactic radiosurgery

AU - Yang, Jun

AU - Qi, Weihua

AU - Wang, Lei

AU - Lu, Qiuxia

AU - Han, Liangfu

AU - Wang, Brian

AU - Yan, Weisi

PY - 2023/12

Y1 - 2023/12

N2 - Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.

AB - Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.

KW - Red Shell

KW - biological equivalent dose

KW - normal tissue

KW - stereotactic radiosurgery

KW - toxicity

UR - https://www.scopus.com/pages/publications/85180515326

UR - https://www.scopus.com/pages/publications/85180515326#tab=citedBy

U2 - 10.1002/pro6.1218

DO - 10.1002/pro6.1218

M3 - Review article

AN - SCOPUS:85180515326

SN - 2398-7324

VL - 7

SP - 273

EP - 277

JO - Precision Radiation Oncology

JF - Precision Radiation Oncology

IS - 4

ER -

Red shell- high risk normal tissue in stereotactic radiosurgery

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

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